Providing open-label placebos remotely-A randomized controlled trial in allergic rhinitis. [PDF]
PLoS ONE, 2021 BackgroundPlacebos can reduce physical symptoms even when provided with full honesty and disclosure. Yet, the precise mechanisms underlying the effects of "open-label placebos" (OLPs) have remained subject of debate.
Tobias Kube +3 more
doaj +2 more sources
Correction: Providing open-label placebos remotely-A randomized controlled trial in allergic rhinitis. [PDF]
PLoS ONE, 2021 [This corrects the article DOI: 10.1371/journal.pone.0248367.].
Tobias Kube +3 more
doaj +2 more sources
Open-label Placebos for Wound Healing: A Randomized Controlled Trial [PDF]
Annals of Behavioral Medicine, 2018 Open-label placebos are a novel treatment option, in which participants take placebos with full knowledge that they do not contain active medicine. Open-label placebo treatments have been shown to result in patient-reported symptom improvements, but they have not been tested on objectively measurable physiological outcomes such as wound healing.The ...
Paul Jarrett +2 more
exaly +3 more sources
Effects of open-label placebos in clinical trials: a systematic review and meta-analysis [PDF]
Scientific Reports, 2021 Open-label placebos (OLPs) are placebos without deception in the sense that patients know that they are receiving a placebo. The objective of our study is to systematically review and analyze the effect of OLPs in comparison to no treatment in clinical ...
Melina von Wernsdorff +3 more
doaj +2 more sources
Open-label placebos—a systematic review and meta-analysis of experimental studies with non-clinical samples [PDF]
Scientific Reports, 2023 The use of open-label placebos (OLPs) has shown to be effective in clinical trials. We conducted a systematic review and meta-analysis to examine whether OLPs are effective in experimental studies with non-clinical populations. We searched five databases
Lukas Spille +4 more
doaj +2 more sources
Open-label placebos reduce hair cortisol concentrations and psychological distress - a randomized controlled trial [PDF]
Scientific ReportsThe exposure to stressful events, such as demanding university exams, is associated with psychological distress and elevated physiological stress responses, which may impair performance.
Carolin Liedtke +2 more
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Effects of Open-Label Placebos on Visual Food Cue Reactivity in Children and Adolescents [PDF]
ChildrenBackground: A high level of food cue reactivity (FCR) is a risk factor for overeating and weight gain. This randomized trial investigated whether open-label placebos (OLPs: placebos honestly administered) can reduce FCR (reported appetite) in children ...
Anne Schienle +4 more
doaj +2 more sources
JAMA Netw OpenImportancePlacebo effects contribute substantially to the therapeutic success of many treatments, particularly in pain-related conditions. Open-label placebos (OLPs) offer an ethically acceptable approach to harness this potential without deception.ObjectiveTo evaluate the efficacy of a 3-month OLP regimen in reducing headache and migraine days and ...
Kleine-Borgmann J +6 more
europepmc +5 more sources
Acceptance of Open-Label Placebos Is Linked to Holistic Health Beliefs and Thinking Styles [PDF]
Behavioral SciencesOpen-label placebos (OLPs) have demonstrated benefits across multiple conditions; however, the factors influencing their acceptance or rejection remain unclear.
Arved Seibel +2 more
doaj +2 more sources
Open-label placebos for menopausal hot flushes: a randomized controlled trial. [PDF]
Sci Rep, 2020 AbstractThis study investigated the efficacy of an open-label placebo (OLP) treatment for menopausal hot flushes. Women with at least five moderate or severe hot flushes per day were allocated to receive four weeks of OLP for twice a day or no-treatment. Intention-to-treat analyses included n = 100 women.
Pan Y +5 more
europepmc +4 more sources