Results 81 to 90 of about 173,890 (311)

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

open access: yesFEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan   +6 more
wiley   +1 more source

The closure of Michael Colliery in 1967 and the politics of deindustrialization in Scotland [PDF]

open access: yes, 2015
Michael Colliery in east Fife was the largest National Coal Board (NCB) unit in Scotland when it closed in 1967, following a disastrous fire which killed nine miners.
Phillips, Jim
core   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

High slope waste dumps – a proven possibility [PDF]

open access: yes, 2013
This paper is an overview of dumping operations on High Slope Waste Dump at Veliki Krivelj open pit copper mine, RTB Bor, Serbia. The High Slope Waste Dump in Bor is the highest single slope waste dump in the world with the slope height of 405 m.
Dejan Petrović   +4 more
core  

Optimization of position of the cyclical-and-continuous method complexes when cleaning-up the deep iron ore quarries [PDF]

open access: yes, 2019
Purpose. An algorithm development for calculating the optimum depth for cyclical-and-continuous method schemes introduction when cleaning-up the deep iron ore quarries. Methods. When developing an algorithm for calculating the optimum depth for cyclical-
Adamchuk, A   +5 more
core   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

Research on construction method of information knowledge map of penetration and explosion in open-pit mining

open access: yesMeitan xuebao
As a complex system engineering, open-pit mining has many business categories, complex system structure and complex information logic relationship. In the process of intelligent upgrading and transformation of open-pit mines, many bottleneck problems ...
Zhao ZHANG, Ruixin ZHANG
doaj   +1 more source

The mining rate in open pit mine planning [PDF]

open access: yes, 2015
In the mining business, mine planning is the activity that determines the exploitation of a mineral resource with the aim of maximising its intrinsic value. The number of variables that are required to carry out this activity and the complexity of dealing with a finite, non-renewable resource make it difficult to find an optimum solution.
openaire   +2 more sources

Wpływ optymalizacji kopalń odkrywkowych na rozwiązanie modelu bilateralnego monopolu: kopalnia & elektrownia w długim okresie [PDF]

open access: yes
THE INFLUENCE OF LIGNITE OPENCAST MINE OPTIMISATION ON SOLUTION OF BILATERAL MONOPOLY MODEL OF LIGNITE MINE & POWER PLANT IN LONG RUN The classical and modified solution of bilateral monopoly for the system of opencast mine and power plant has been ...
Jurdziak, Leszek
core   +1 more source

Observation and auscultation of the geotechnical behaviour of a slope in an open cast mine influenced by old underground mining (South-western part of France) [PDF]

open access: yes, 1993
International audienceThe final slopes of a French open pit mine of the "Charbonnage de France" Company which final depth will be 300 metres, have been designed after a Standard geotechnical survey.
Driancourt, Didier   +3 more
core   +1 more source

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