Results 111 to 120 of about 2,099,286 (284)
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
The Land Conservation Plan for Maine’s Piscataqua Region Watersheds [PDF]
, 2010 The Piscataqua River/Great Bay estuary is a shared coastal embayment that forms the southernmost boundary between the states of Maine and New Hampshire.
Czapiga, Jason +6 more
core +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Delivering on Open Government: The Obama Administration's Unfinished Legacy [PDF]
, 2013 This report examines progress made during President Obama's first term toward open government goals outlined in a comprehensive set of recommendations that the open government community issued in November 2008, titled Moving Toward a 21st Century Right ...
Gavin Baker, Sean Moulton
core
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Spatiality and transpatiality in workplace environments [PDF]
, 2009 It is widely considered that the physical layout of workplace environments has an influence on social interaction and therefore the social structure of an organisation.
Penn, A., Sailer, K.
core
Probabilistic Hybrid Action Models for Predicting Concurrent Percept-driven Robot Behavior
, 2005 This article develops Probabilistic Hybrid Action Models (PHAMs), a realistic causal model for predicting the behavior generated by modern percept-driven robot plans.
Beetz, M., Grosskreutz, H.
core +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Teaching robots parametrized executable plans through spoken interaction [PDF]
, 2015 While operating in domestic environments, robots will necessarily face difficulties not envisioned by their developers at programming time. Moreover, the tasks to be performed by a robot will often have to be specialized and/or adapted to the needs of
BASTIANELLI, EMANUELE +2 more
core
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source