Results 91 to 100 of about 821,108 (308)
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Evidence-Based Design: Theoretical and Practical Reflections of an Emerging Approach in Office Architecture [PDF]
, 2009 Evidence-based design is a practice that has emerged only relatively recently, inspired by a growing popularity of evidence-based approaches in other professions such as medicine.
Budgen, Andrew +4 more
core
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
WRI's Governance Strategy, 2016-2020 [PDF]
, 2016 Transparent, effective, accountable governance is critical to ensuring that development benefits people and the planet. The Governance Center of Excellence works with civil society, governments, development agencies, businesses, and other institutions to
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Thermal Comfort and Adaptive Occupant Behaviour in Open Plan Offices in India and Lithuania
BuildingsUnderstanding the relationship between thermal comfort and adaptive behaviour in office environments is important for designing sustainable and occupant-centric buildings.
Himanshu Patel Tuniki +4 more
doaj +1 more source
Development of a Bayesian based adaptive optimisation algorithm for the thermostat settings in agile open plan offices. [PDF]
Energy Build, 2021 Lin W, Kokogiannakis G.
europepmc +1 more source
How Office Workers Cope with Distraction by Sounds in the Open Plan Office
, 2019 Proceedings of the ICA 2019 and EAA Euroregio : 23rd International Congress on Acoustics, integrating 4th EAA Euroregio 2019 : 9-13 September 2019, Aachen, Germany / proceedings editor: Martin Ochmann, Michael Vorländer, Janina Fels 23rd International Congress on Acoustics, integrating 4th EAA Euroregio 2019, ICA 2019, Aachen, Germany, 9 Sep 2019 - 13 ...
Steps, Sven +3 more
openaire +2 more sources
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Noise Pollution Effects on Mental Fatigue and Noise Annoyance among Bank Staffs
International Journal of Occupational Hygiene, 2019 Noise discomfort is one of the important unpleasant physical parameters in open-plan offices. This study was aimed to investigate the status of noise pollution and its effects on subjective fatigue and noise annoyance among bank staffs.
Mohammad Reza Zare +4 more
doaj