Results 81 to 90 of about 821,108 (308)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Investigation acoustic comfort indexes in staff of open plan offices in state banks in Hamadan city

open access: yesMuhandisī-i bihdāsht-i ḥirfah/ī, 2015
Background & Objectives: Noise is one of the most detrimental factors in working environments that alongside other physical problems have adverse effects on the mental health of employees.
Trifah Nezami   +3 more
doaj  

Health and wellbeing in a deep plan office space [PDF]

open access: yes, 2008
This research tracks public sector employees as they move from a 1960s office building into a purpose-built, environmentally sound, office accommodation.
Brown, Guy, Capper, Graham, Holmes, John
core  

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Optimizing User Distributions in Open-Plan Offices for Communication and Their Implications for Energy Demand and Light Doses: A Living Lab Case Study

open access: yesBuildings
Open-plan offices have established themselves as economically efficient working environments and promote communication. Zoned lighting concepts have proven to be particularly energy-efficient and are determined by the respective occupancy profile. Due to
Sascha Hammes, Johannes Weninger
doaj   +1 more source

FEMA's Integration of Preparedness and Development of Robust Regional Offices [PDF]

open access: yes, 2009
In October 2006, Congress enacted major legislation to reform the function and organization of the Federal Emergency Management Agency (FEMA) in response to the recognized failures in preparation for and response to Hurricane Katrina.
Anthony Griffin   +6 more
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Lighting, well-being and work performance: A review of the literature [PDF]

open access: yes, 2010
Commissioned White Paper Report for Philips ...
Konstantinou, E.   +2 more
core  

Assessing the Medical Emergency Preparedness of Dental Faculty, Residents, and Practicing Periodontists: An Exploratory Study [PDF]

open access: yes, 2018
With the increased number of elderly and medically compromised individuals receiving dental care and the presence of systemic comorbidities and associated treatment modalities in this patient population, it is imperative that dentists be prepared to ...
Blanchard, Steven   +6 more
core   +1 more source

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