Results 151 to 160 of about 1,249,788 (300)

DNA Replication Errors Drive Genome‐Wide Small Inverted Triplication Dynamics

Advanced Science, EarlyView.
This study provides insight into the dynamic equilibrium mechanism of a novel structural variant, small inverted triplication (SIT), which is generated by misalignment of the 3’ flap generated under DNA replication stress with palindromic sequence. Alternatively, the end sequence may fold back on itself to form an inverted fragment.
Yi Lei, Yu Zhou, Haitao Sun, Hang Yuan, Xinyu Pei, Jessica D. Hess, Yao Yan, Zunsong Hu, Mian Zhou, Zhaohui Gu, Li Zheng, Xiwei Wu, Binghui Shen   +12 more
wiley   +1 more source

Oral history project officer, the open university oral history project

, 2008
Open University Archive• Designed and completed an oral history of the organisation with staff and students.• Planned sound archival system and implemented storage methods.
Bornat, Joanna, Cammies, Ruth, Young, Hilary   +2 more
core  

MFPD: A Multiple Fungal Pathogen Detection Pipeline Across Diverse Habitats

Advanced Science, EarlyView.
The MFPD pipeline integrates a comprehensive ITS reference database of fungal pathogens, optimized parameters, and algorithms tailored for both full‐length and subregion sequences that balance accuracy and computational efficiency; it enables high‐throughput, species‐level identification from amplicon sequencing data, supporting large‐scale ...
Yi Shen, Xinrun Yang, Jiabao Yu, Yaozhong Zhang, Tianjie Yang, Yang Gao, Xiaofang Wang, Alexandre Jousset, Waseem Raza, Fang‐Jie Zhao, Qirong Shen, Gaofei Jiang, Zhong Wei, Yangchun Xu   +13 more
wiley   +1 more source

The Trichinella Super‐Pangenome Reveals the Evolution of Encapsulation and Predicted Host–Parasite Protein Interactions

Advanced Science, EarlyView.
ABSTRACT The muscle capsule of Trichinella is a critical structure that impedes immune attacks and drug penetration, yet the molecular mechanisms underlying its formation remain poorly understood. Using a high‐quality super‐pangenome comprising 12 Trichinella species, we compared extensive genomic variations between encapsulating and non‐encapsulating ...
Qingbo Lv, Yi Liu, Ning Xu, Xiao Zhang, Yaming Yang, Chengyao Li, Hanhai Mao, Mingyuan Liu, Xiaolei Liu   +8 more
wiley   +1 more source

OPIA: an open archive of plant images and related phenotypic traits. [PDF]

Nucleic Acids Res
Cao Y, Tian D, Tang Z, Liu X, Liu X, Hu W, Zhang Z, Song S.   +7 more
europepmc   +1 more source

Archiving scientific literature : an experience with e-prints archive software

, 2002
The world of academic publishing is undergoing many changes. Paper based publishing is being supplemented by electronic archives. In certain areas, preprint distribution has completely moved away from the paper-based system in to a fully electronic ...
Jayakanth, Francis, Singhal, Madhuresh
core  

NQO1‐Mediated Anoikis Resistance and Immune Evasion Define a High‐Risk Multi‐Omic Subtype for Precision Management of T1 High‐Grade Bladder Cancer

Advanced Science, EarlyView.
Multi‐omic profiling of T1 high‐grade bladder cancer identifies a high‐risk subtype (T1HG1) driven by NQO1, which couples anoikis resistance with immune evasion. NQO1 orchestrates macrophage–T cell crosstalk suppression via CXCL9 modulation. Pharmacological NQO1 inhibition with skullcapflavone II enhances cisplatin efficacy, representing a promising ...
Bin Guo, Chunru Xu, Shufan Fu, Qiang Cheng, Juan Li, Linkuo Shang, Gaojie Li, Yang Yang, Ying Wang, Yanqing Gong, Shengwei Xiong, Jian Fan, Changwei Yuan, Mei Zhang, Yifan Zuo, Elena Papaleo, Yue Shi, Yuan Liang, Xuesong Li, Hongzhao Li, Weimin Ci   +20 more
wiley   +1 more source

Multi‐Omics Insights Into the Mechanisms of Early Muscle Fiber Difference and Transformation Between Lean‐Type and Chinese Indigenous Pigs

Advanced Science, EarlyView.
Multi‐omics analyses uncover breed‐specific cis‐regulatory landscapes and higher‐order chromatin architectural differences that underlie early postnatal muscle fiber divergence in pigs. A super‐enhancer upstream of PPP3CB recruits MEF2C to activate PPP3CB transcription, while the PPP3CB–MEF2C positive feedback loop promotes oxidative muscle fiber ...
Shuailong Zheng, Hainan Wu, Min Liu, Kunpeng Wu, Shuntao Huang, Zulfiqar Ahmed, Lenox Pius, Mengjin Zhu, Dequan Xu   +8 more
wiley   +1 more source

Pooling data from studies on prolonged grief: the Multi-region Archive of Research data on Bereavement and Loss from Empirical Studies (MARBLES) project. [PDF]

Eur J Psychotraumatol
Boelen PA, Baş S, Bolaséll LT, Bryant RA, Cesur-Soysal G, Eisma MC, Goodfellow B, De Keijser J, Kersting A, Keser E, O'Connor M, Prigerson HG, Schut B, Vissers I, Tang S, Treml J, Van Tuijl LA, Wang J, Asberg L, Lechner-Meichsner F, Xie C, Xu X, Lenferink LIM.   +22 more
europepmc   +1 more source

Umfrage: Von Open Access zu Open Science - Wissenschaftliche Kommunikation im Rahmen der Digitalisierung

Wie verändert die Digitalisierung, wie wir auf wissenschaftliche Daten und Informationen zugreifen? Das war Thema in der Befragung im Rahmen der Promotion mit dem Titel: "Von Open Access zu Open Science: Zum Wandel von wissenschaftlicher Kommunikation ...
Heise, Christian, Leuphana Universit\ue4t / Cent\uadre for Di\uadgi\uadtal Cul\uadtu\uadres
core   +1 more source