Results 161 to 170 of about 26,317,005 (275)

ZMIZ2–DUX4–LGR5 Signaling Axis Maintains Stemness Properties and Facilitates Docetaxel Resistance in Triple‐Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
This study identifies ZMIZ2 as a therapeutic target for docetaxel‐resistant triple‐negative breast cancer, sustaining cancer stemness‐associated properties and docetaxel resistance. ZMIZ2 upregulation enhances DUX4‐mediated LGR5 activation through the SWI/SNF components BRG1 and BAF57.
Xueting Gan   +9 more
wiley   +1 more source

Shotgun metagenomic dataset of surface microbiomes at a train station in Shinagawa, Tokyo. [PDF]

open access: yesBMC Genom Data
Gao X   +5 more
europepmc   +1 more source

Atlas‐Guided CD55‐Enriched Neutrophil Extracellular Vesicles for Complement–Macrophage Modulation in Diabetic Wounds

open access: yesAdvanced Science, EarlyView.
ABSTRACT Diabetic wounds are characterized by persistent inflammation and impaired immune resolution, yet the therapeutic translation of single‐cell atlases into rational immunomodulatory strategies remains limited. Here, integration of diabetic‐wound single‐cell transcriptomic datasets identifies a neutrophil subpopulation enriched in cluster of ...
Tairong Cui   +12 more
wiley   +1 more source

Clinical Features, Treatments, and Outcomes of an International Cohort of 96 Children with Takayasu Arteritis. [PDF]

open access: yesACR Open Rheumatol
Bistolarides J   +29 more
europepmc   +1 more source

Acinar‐Derived Organoids Reveal Stage‐Specific Control of Acinar Plasticity

open access: yesAdvanced Science, EarlyView.
An acinar‐derived organoid system maintains adult pancreatic acinar identity ex vivo, converts it along an ordered acinar‐to‐ductal‐like trajectory, and then partially restores it. Each transition carries its own signal requirement, with EGF/EGFR initiating conversion and a staged glucocorticoid–IGF1R switch driving redifferentiation.
Yongfei Hou   +10 more
wiley   +1 more source

Fundamentos tecnológicos del acceso abierto : Open Archives Initiative y Open Archival Information System

open access: yes, 2005
The aim of this paper is to analyse the technological foundations of both open access and digital archives preservation. First, a discussion is offered of the Open Archives Initiative, which was developed to facilitate the discovery of content stored in distributed archives.
openaire   +1 more source

Long‐Term Expandable Periosteal Organoids Reconstruct a Functional Regenerative Niche That Support Hematopoietic Stem Cell Maintenance and Bone Repair

open access: yesAdvanced Science, EarlyView.
A robust periosteal organoid system enables long‐term expansion while preserving native cellular heterogeneity. These organoids recapitulate functional niche environments, support hematopoietic stem cell maintenance, and attenuate aging‐associated decline ex vivo.
Jia Qing   +9 more
wiley   +1 more source

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