Results 41 to 50 of about 841,164 (237)

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Distribution of motion scales of vortices in turbulent open channel flow

Shui kexue jinzhan, 2015
To understand the distribution of motion scales of vortices in turbulent open channel flow along water depth. A flume experiment system based on high-resolution particle image velocimetry(PIV) was applied to measure fully developed turbulent open channel
ZHANG Peng, YANG Shengfa, HU Jiang, CHEN Yang, XING Yun   +4 more
doaj   +1 more source

Inverse task of pollution spreading – Localization of source in extensive open channel network structure

Journal of Hydrology and Hydromechanics, 2023
This paper is focused on the problem of the pollutant source localisation in streams in other words the solution of the inverse problem of pollution spreading with in an extensive open channel network structure, i.e.
Velísková Yvetta, Sokáč Marek, Moghaddam Maryam Barati   +2 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

An experimental study of non-Newtonian fluid flow in rectangular flumes in laminar, transition and turbulent flow regimes

Journal of the South African Institution of Civil Engineers, 2010
New and extensive results are reported on the flow of a range of non-Newtonian fluids, including aqueous suspensions of bentonite and kaolin, and aqueous solutions of synthetic polymer carboxymethyl cellulose (CMC), flowing down inclined flumes of ...
R Haldenwang, P T Slatter, R P Chhabra
doaj  

Simulation of mixed convection of a variable viscosity fluid in a partially porous horizontal channel with a heat-generating source [PDF]

Компьютерные исследования и моделирование, 2019
Numerical study of unsteady mixed convection in an open partially porous horizontal channel with a heatgenerating source was performed. The outer surfaces of horizontal walls of finite thickness were adiabatic.
Marina Sergeevna Astanina, Mikhail Aleksandrovich Sheremet   +1 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source