Results 41 to 50 of about 791,234 (283)

Single-channel behavior of heteromeric α1β glycine receptors: an attempt to detect a conformational change before the channel opens [PDF]

open access: yes, 2004
The α1β heteromeric receptors are likely to be the predominant synaptic form of glycine receptors in the adult. Their activation mechanism was investigated by fitting putative mechanisms to single-channel recordings obtained at four glycine ...
Burzomato, V.   +4 more
core  

A predefined channel coefficients library for vehicle-to-vehicle communications [PDF]

open access: yes, 2015
It is noticeable that most of VANETs communications tests are assessed through simulation. In a majority of simulation results, the physical layer is often affected by an apparent lack of realism.
Turner, Scott J   +5 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Open Channel Hydraulics [PDF]

open access: yes, 2021
Open Channel Hydraulics, Second Edition provides extensive coverage of open channel design, with comprehensive discussions on fundamental equations and their application to open channel hydraulics.
Iyer, Seshadri, Akan, A. Osman
core  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Modelling rollers for shallow water flows [PDF]

open access: yes, 2013
Hydraulic jumps, roll waves or bores in open channel flows are often treated as singularities by hydraulicians while slowly varying shallow water flows are described by continuous solutions of the Saint-Venant equations. Richard & Gavrilyuk (J.
Thual, Olivier
core   +1 more source

Computational fluid dynamics simulation of rough bed open channels using openFOAM

open access: yesFrontiers in Environmental Science, 2022
With increased flood risk due to climate change, population expansion and urbanisation; robust waterway design and management are critical. One common type of waterway used to gather and transport ground water is the open channel. Most simulations do not
Yun-Hang Cho   +3 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Estimation of Form Drag Caused by Rigid Vegetation Based on Equivalent Roughness

open access: yesIEEE Access, 2019
The flow structure over vegetation in ecological channel is rather complex and the resistance caused by vegetation is affected by many factors, such as discharge, flow depth, vegetation density and patch arrangement types, etc.
Xiao-Dong Liu   +5 more
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

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