Results 61 to 70 of about 2,178,021 (284)

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Experimental Investigation on the Performance Analysis of a Constructed Hydro-Powered Coil Pump

Engineering Transactions
A hydro-powered water pumping system is one of the most important systems for upland areas in terms of supplying water for irrigation and daily usage.
Md. Alamgir HOSSAIN, Minhaj RAHMAN, Shariful Islam FAHAD   +2 more
doaj   +1 more source

Unitarity Meets Channel-Duality for Rolling / Decaying D-Branes [PDF]

, 2006
Investigations for decay of unstable D-brane and rolling of accelerated D-brane dynamics have revealed that various proposed prescriptions give different result for spectral amplitudes and observables.
A. Maloney, A. Sen, A. Sen, A. Strominger, A. Strominger, A.B. Zamolodchikov, B. Chen, B. Craps, B. Durin, B. Pioline, C. Bachas, chapter 6 of C. Itzykson, D. Bak, D. Kutasov, D. Kutasov, D.A. Sahakyan, H. Liu, H. Liu, I.R. Klebanov, J. Simon, J.L. Karczmarek, K. Okuyama, K. Okuyama, M. Berkooz, M. Gutperle, N. Lambert, R.C. Myers, S. Elitzur, S. Ribault, S.J. Rey, S.J. Rey, Soo-Jong Rey, T. Eguchi, T.G. Erler, V. Fateev, V. Schomerus, Y. Hikida, Y. Nakayama, Y. Nakayama, Y. Nakayama, Y.I. Kogan, Yu Nakayama, Yuji Sugawara   +42 more
core   +3 more sources

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Voltage-dependent Block of the Cystic Fibrosis Transmembrane Conductance Regulator Cl- Channel by Two Closely Related Arylaminobenzoates [PDF]

, 1993
The gene defective in cystic fibrosis encodes a Cl- channel, the cystic fibrosis transmembrane conductance regulator (CFTR). CFTR is blocked by diphenylamine-2-carboxylate (DPC) when applied extracellularly at millimolar concentrations.
Cohen, B. N., Davidson, N., Lester, H. A., McCarthy, N. A., McDonough, S., Riordan, J. R.   +5 more
core  

On the Spectrum of Large Random Hermitian Finite-Band Matrices

, 2008
The open problem of calculating the limiting spectrum (or its Shannon transform) of increasingly large random Hermitian finite-band matrices is described. In general, these matrices include a finite number of non-zero diagonals around their main diagonal
Poor, H. Vincent, Shamai, Shlomo, Simeone, Osvalso, Somekh, Oren, Zaidel, Benjamin M.   +4 more
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Nonlinear hopping transport in ring systems and open channels

, 2009
We study the nonlinear hopping transport in one-dimensional rings and open channels. Analytical results are derived for the stationary current response to a constant bias without assuming any specific coupling to the external fields.
Abraham Nitzan, Ambegaokar, Berneche, Berneche, Datta, Derrida, Derrida, Evans, Frey, Glauber, Gouyet M. Plapp, Graf, Hager, Harris, Harris, Heuer, Hille, Kehr, Kohli, Kollmann, Krug, Kunow, Maass, Maass, MacDonald, Mario Einax, Martin Körner, Mott, Murugavel, Nitzan, Nitzan, Philipp Maass, Roling, Roling, Romano, Schütz, Spohn, Tripathy, van Beijeren, Xu, Zilman   +40 more
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Optimized ANFIS-Genetic Algorithm-Particle Swarm Optimization Model for Estimation of Side Orifices Discharge Coefficient [PDF]

Numerical Methods in Civil Engineering, 2018
Generally, side orifices are installed on side walls of the main channels for regulating and controlling water. In this study, a novel hybrid model was developed in order to estimate discharge coefficient of circular and rectangular side orifices.
A. H. Azimi, A. Rajabi, S. Shabanlu
doaj   +1 more source