Results 71 to 80 of about 1,103,131 (296)

Discrete element study of liquid-solid slurry flows through constricted channels [PDF]

, 2009
Discrete element model is used to simulate the flow of liquid-granule mixtures in an inclined channel containing a linear contraction. All the relevant particle/particle and particle/fluid interactions are included in the numerical model. The presence of
Abbas, Micheline, Bokhove, Onno, Hoef, Martin van der, Kuipers, Hans   +3 more
core   +4 more sources

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Design of Mine-used Ultrasonic Open-channel Flowmeter

Gong-kuang zidonghua, 2011
In view of problem that open-channel flowmeter ca't work normally because mine water contains impurities of coal powder and sediment which deposit on surface of probe of open-channel flowmeter, a mine-used ultrasonic open-channel flowmeter based on M-Bus
XU Le-nian, LIU Wei-guang, WANG Quan
doaj  

Measurement of turbulent flow in a narrow open channel

Journal of Hydrology and Hydromechanics, 2016
The paper presents the experimental results of turbulent flow over hydraulically smooth and rough beds. Experiments were conducted in a rectangular flume under the aspect ratio b/h = 2 (b = width of the channel 0.5 m, and h = flow depth 0.25 m) for both ...
Sarkar Sankar
doaj   +1 more source

Wireless Network Control with Privacy Using Hybrid ARQ

, 2012
We consider the problem of resource allocation in a wireless cellular network, in which nodes have both open and private information to be transmitted to the base station over block fading uplink channels.
Ercetin, Ozgur, Erçetin, Özgür, Koksal, Can Emre, Köksal, Can Emre, Sarıkaya, Yunus, Sarikaya, Yunus   +5 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

STUDY OF THE NEWTON RAPHSON METHOD IN ANALYZING THE DEPTH OF FLUID FLOW IN THE WASTEWATER CANAL U RPS TKRO SMKN 1 CIRUAS USING THE MATLAB APPLICATION

Jurnal Teknik Mesin
--Flow Depth can be defined as channel height or open channel flow depth, is an important parameter in hydraulic calculations and analysis. The depth of flow in the U channel (U channel) of the Student Practice Room (RPS) for Automotive Light Vehicle ...
rdwi pudji susilo
doaj   +1 more source

Monitoring of Sediment Deposition in the Open Channel of a Coal Mine Based on Measuring　Robot

Meikuang Anquan, 2020
Based on the dynamic monitoring of the water flow in the underground open channel of Yaoqiao Coal Mine, a robot is designed that can automatically measure the sediment thickness of the open channel to solve the problem of inaccurate measurement of open ...
XU Lenian, HUAN Zhihao, YAN Maoyin
doaj   +1 more source