Results 101 to 110 of about 853,817 (299)

Employer support for health and social care registered professionals, their patients and service users involved in regulatory fitness to practise regulatory proceedings

BMC Health Services Research
Background Health and social care employees may be involved in professional regulatory proceedings because their alleged behaviour raises health or conduct concerns.
Louise M Wallace, Mari Greenfield
doaj   +1 more source

Socioeconomic status and educational inequality: digital competency pathways to creative problem-solving and academic performance

Frontiers in Psychology
IntroductionThe digital divide extends beyond technology access to create educational inequalities through differential competency development, where socioeconomic advantages enable sustained digital engagement that enhances creative problem-solving ...
Jinglu Liu, Yuwei Chen
doaj   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Supporting Open Practices with Teachers in Zambia

Journal of Learning for Development, 2019
This paper demonstrates how the features and affordances of open learning have been developed in new and productive ways to provide school-based continuing professional development for teachers in Zambia. It presents and critically reviews data from 200
Kris Stutchbury, Lore Gallastegi, Clare Woodward   +2 more
doaj  

2021 OE Week UC San Diego Student Open Education Initiatives & California's Higher Education Collaborative OER Efforts

, 2021
Sky-Lauryn White, Aanvi Jhaveri, Allegra Swift, Cianna N. Calia, Michelle Pilati, Dave Dillon   +5 more
openalex   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Engagement of health and social care employers in professional regulatory fitness to practise – missed regulatory and organisational opportunities?

BMC Health Services Research
Background Health and social care professional regulators are organisations that ensure their registrants have the correct qualifications and experience to practise in their profession.
Louise M. Wallace, Mari Greenfield
doaj   +1 more source

‘I have to pretend that I don’t care’: Stigma management among unmarried young mothers in South-Western Nigeria

Global Public Health
Young mothers often encounter stigma and discrimination, affecting their lives and that of their children. This paper explores stigma management strategies and their effectiveness for young mothers in rural Nigeria.
Ayomide Oluseye, Philippa Waterhouse, Lesley Hoggart   +2 more
doaj   +1 more source