A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Integrating open education practices with data analysis of open science in an undergraduate course. [PDF]
Bakermans MH.
europepmc +1 more source
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Book Review: Building Knowledge Cultures: Education and Developments in the Age of Knowledge Capitalism, Constraining Public Libraries: The World Trade Organization's General Agreement on Trade in Services, Libr@ries: Changing Information Space and Practice, Open Source Database Driven Web Development: A Guide for Information Professionals [PDF]
Ruth Rikowski +3 more
openalex +1 more source
Open education needs open scholarship
Gavin Baker will be blogging on open education and open access at Terra Incognita, the online education blog at Penn State University. PS: Gavin is sharp on these issues. I’ll be tuning in.
openaire +1 more source
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
IUPAC International Chemical Identifier (InChI)-related education and training materials through InChI Open Education Resource (OER). [PDF]
Cornell AP +6 more
europepmc +1 more source
Moons: a MOOC and open education resource with games and a microscope [PDF]
S. P. Kelley +2 more
openalex

