Results 141 to 150 of about 2,886,776 (296)
Open data and the core competences of government : lessons from Flanders, Belgium [PDF]
, 2019 Ballon, Pieter +4 more
core +2 more sources
Governance in the age of social machines: the web observatory [PDF]
The World Wide Web has provided unprecedented access to information; as humans and machines increasingly interact with it they provide more and more data. The challenge is how to analyse and interpret this data within the context that it was created, and
Andy Koronios +9 more
core
Open government, open data : l’empowerment citoyen en question
, 2017 La multiplication des initiatives d’ouverture des données publiques et des plans d’action relatifs à l’open government a suscité de nombreux questionnements autour de leur capacité effective à renforcer le pouvoir d’agir des citoyens et des citoyennes.
openaire +2 more sources
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Licensing Open Government Data
This article focuses on the legal issues associated with open government data licenses. This study compares current open data licenses and argues that licensing terms reflect policy considerations, which are quite different from those contemplated in business transactions or shared in typical commons communities. This article investigates the ambiguous
openaire +2 more sources
Open Data Stakeholders: Governments
, 2019 Chapter 26 in the book The State of Open Data: Histories and Horizons.
openaire +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Reliability analyses of open government data
CEUR Workshop Proceedings, 2013 Public authorities are increasingly sharing sets of open data. These data are often preprocessed (e.g. smoothened, aggregated) to avoid to expose sensible data, while trying to preserve their reliability. We present two procedures for tackling the lack of methods for measuring the open data reliability.
Ceolin, Davide +7 more
openaire +2 more sources
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source