Results 141 to 150 of about 2,286,604 (339)

Enabling and Sustaining Collaborative Innovation [PDF]

open access: yes
This paper extends the principles of open source software development to a non-industry-specific level by introducing the Open Source Innovation (OSI) model.
Abdelkafi, Nizar   +2 more
core   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

Interplay between RNA‐protein interactions and RNA structures in gene regulation

open access: yesFEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko   +2 more
wiley   +1 more source

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

open access: yesFEBS Open Bio, EarlyView.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source

Motivation and Sorting in Open Source Software Innovation [PDF]

open access: yes
This paper studies the role of intrinsic motivation, reputation, and reciprocity in driving open source software innovation. Unlike previous literature based on survey data, we exploit the observed pattern of contributions - the .revealed preference.
Mark Schankerman, Sharon Belenzon
core  

Open Access Pump-Priming Expenditure Report University of Glasgow [PDF]

open access: yes, 2013
Report on activity undertaken with a grant of £360k from the Department for Business, Innovation and Skills in support of Open Access to research ...
McCutcheon, V.
core  

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

open access: yesFEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul   +3 more
wiley   +1 more source

Is 'Open Innovation' Re-Inventing Innovation Policy for Catching-up Economies? [PDF]

open access: yes
This paper discusses the current state of the .open innovationÿ thinking in the context of core economic challenges faced by catching-up and developing countries. The main argument of the paper is that due to the paradoxes and contradictions between the .
Erkki Karo, Rainer Kattel
core  

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