Results 151 to 160 of about 788,297 (312)
FEBS Open Bio, EarlyView.Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu +10 more
wiley +1 more source
Open Innovation as the Catalyst in the Personalized Medicine to Personalized Digital Medicine Transition. [PDF]
J Pers Med, 2022 Cesario A +5 more
europepmc +1 more source
FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
, 2010 Just what is innovation? This unit examines the issues surrounding the concept of innovation. What is the difference between innovation and invention? How are organisations affected by innovation: are all of the outcomes positive?
Open University
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Broker roles in open innovation
Knowledge brokers play a crucial role in open innovation. We use exponential random graph models and qualitative analysis of semi-structured interview data to contrast knowledge brokerage in three open innovation partnerships. Our analysis considers both
Wang, P. +4 more
core +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Linking solver characteristics, solving processes and solution attributes: A data explainer for an open innovation generated robotic design dataset. [PDF]
Data Brief, 2023 Szajnfarber Z +4 more
europepmc +1 more source
Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
Open innovation during the COVID-19 pandemic policy responses in South Africa and Kenya. [PDF]
Polit Policy, 2022 Onyango G, Ondiek JO.
europepmc +1 more source
Public firm sponsorship of open source software: A knowledge-based approach to open innovation
, 2011 As an emerging innovation paradigm gaining momentum in recent years, the open innovation paradigm is calling for greater theoretical depth and more empirical research. This dissertation proposes that open innovation in the context of open source software
Lan, Sai
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