Overview of molecular signatures of senescence and associated resources: pros and cons
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
Linking solver characteristics, solving processes and solution attributes: A data explainer for an open innovation generated robotic design dataset. [PDF]
Szajnfarber Z +4 more
europepmc +1 more source
Construction of Open Innovation Ecology on the Internet: A Case Study of Xiaomi (China) Using Institutional Logic [PDF]
Jaime Ortiz, Hao Ren, Kei Li, An Zhang
openalex +1 more source
Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner +6 more
wiley +1 more source
Open Innovation as the Catalyst in the Personalized Medicine to Personalized Digital Medicine Transition. [PDF]
Cesario A +5 more
europepmc +1 more source
Open, distributed and user-centered: Towards a paradigm shift in innovation policy [PDF]
Today's innovation policies ignore that innovation is increasingly open, distributed and user-centered. In this paper we introduce the user-centered model as an alternative paradigm of how innovation 'works'.
Eric von Hippel, Jeroen de Jong
core
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani +7 more
wiley +1 more source
Open innovation during the COVID-19 pandemic policy responses in South Africa and Kenya. [PDF]
Onyango G, Ondiek JO.
europepmc +1 more source
T2K Open Supercomputer and Industrial Use for Innovation
Yutaka Ishikawa +2 more
openalex +2 more sources

