Developing a framework for measuring open innovation in defense industry [PDF]
بهبود مدیریت, 2019 Evidence in defense industry including knowledge dispersion and budget cuts demonstrate increasingly necessity of moving toward open innovation as defense industry in united states of America, England, and many other countries are opening their ...
Ebrahim Sozanchi Kashani +2 more
doaj
Intrapreneurial Fit and Misfit: Enterprising Behavior, Preferred Organizational and Open Innovation Culture [PDF]
, 2021 Nick Chandler, Zoltán Krajcsák
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Open innovation processes in living lab innovation systems: insights from the LeYLab [PDF]
, 2013 Living labs have emerged on the crossroads of the open innovation and user innovation frameworks. As open innovation systems, living labs consist of various actors with each playing their specific role.
Ballon, Pieter +2 more
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Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
User, and Open Collaborative Innovation: Ascendent Economic Models [PDF]
In this paper we assess the economic viability of innovation by producers relative to two increasingly important alternative models: innovations by single user individuals or firms, and open collaborative innovation projects.
Carliss Y. Baldwin, Eric von Hippel
core
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Public Policies, Open Innovation Ecosystems and Innovation Performance. Analysis of the Impact of Funding and Regulations [PDF]
, 2022 Joana Costa, António Carrizo Moreira
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More open than open innovation? Rethinking the concept of openness in innovation studies. [PDF]
This paper re-examines the concept of open innovation developed in organization sciences (Chesbrough, 2003a). We claim that this paradigm, which insists on the distributive nature of innovation among a wide range of heterogeneous actors, does not put ...
Julien Pénin
core
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Outlier Detection for Minor Compositional Variations in Taxonomic Abundance Data
Applied Sciences, 2019 To understand the activities of complex microbial communities in various natural environments and living organisms, we need to capture the compositional changes in their taxonomic abundance.
Koji Ishiya, Sachiyo Aburatani
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