Results 91 to 100 of about 788,297 (312)
Open Innovation Success Factors by ICT Use in Japanese Firms [PDF]
The innovation by an independence principle is a limit in Japanese firm today. The expectation for the open innovation that positively uses outside resources on business has risen in Japanese firm.
Idota, Hiroki +2 more
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Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Open Innovation: Organizational Challenges of a New Paradigm of Innovation Management [PDF]
The goal of this paper is to analyze the main problems that emerge from the open innovation model. Adopting as analytical framework an organizational perspective we divide the main challenges that arise from the management of open innovation in two main ...
José López RODRÍGUEZ +1 more
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TCT innovation taxonomy and open foresight innovation paradigm
This paper presents a novel taxonomy for the review of literature specifically in the field of Science Fiction Prototyping (SFP) and Foresight Innovation.
Ward, G., Jaddoa, A.
core +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
User, and Open Collaborative Innovation: Ascendent Economic Models [PDF]
In this paper we assess the economic viability of innovation by producers relative to two increasingly important alternative models: innovations by single user individuals or firms, and open collaborative innovation projects.
Eric von Hippel, Carliss Y. Baldwin
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KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Living Labs as Tools for Open Innovation [PDF]
This paper presents a Living Lab in Stockholm as a focal point for discussing how the Living Lab concept can be extended and used for engaging in multiorganizational open innovation.
Niklas Z. KVISELIUS +3 more
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Open Innovation in Universities: The Relationship Between Innovation and Commercialisation
, 2014 Increasing calls from university stakeholders to optimise innovation capabilities has never been more urgent given the increasing link between industry and universities.
David Roberts +5 more
core +1 more source