Results 71 to 80 of about 16,123,195 (290)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Ohio's open government laws

open access: yes, 2004
Title from screen 1, right panel (viewed Oct. 8, 2004).; "Auditor of State, Betty Montgomery."; Electronic text (pdf, 2 p.).; Harvested from the web on 10/8 ...
Ohio. Open Government Unit
core  

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Creating open educational resources

open access: yes, 2010
Are you interested in creating your own open educational resources? This unit will help you to write a learning unit and provide you with links to various resources for open-learning materials.
Open University
core  

Long term stability of learning outcomes in undergraduates after an open-inquiry instruction on thermal science

open access: yesPhysical Review Physics Education Research, 2018
This paper investigates the efficacy of an open-inquiry approach to achieve a long term stability of physics instruction. This study represents the natural continuation of a research project started four years ago when a sample of thirty engineering ...
Dominique Persano Adorno   +2 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Philosophical Inquiry to Advance Cosmopolitan Engagement

open access: yes, 2012
Il progetto intende promuovere lo sviluppo di attitudini, competenze, stili di pensiero caratterizzati dalla capacità di essere riflessivamente consapevoli delle proprie radici e della propria identità e allo stesso tempo di aprirsi al nuovo e al ...
Camhy D.   +3 more
core  

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Flanagan may open inquiry into Garda drug collusion allegations.

open access: yes, 2017
Justice Minister Charlie Flanagan has signalled the establishment of an inquiry into allegations of Garda collusion in the heroin trade. ..
O'Connor, Niall
core  

Home - About - Disclaimer - Privacy