Results 81 to 90 of about 16,123,195 (290)

Open Inquiry versus Broadly Relevant Short-Term Research Experiences for Non-Biology Majors. [PDF]

open access: yesJ Microbiol Biol Educ, 2021
Hebert S   +5 more
europepmc   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Multimedia-Based Assessment of Scientific Inquiry Skills: Evaluating High School Students’ Scientific Inquiry Abilities Using Cloud Classroom Software

open access: yesEngineering Proceedings
We developed and validated an animation-based assessment (ABA) method for evaluating high school students’ inquiry competencies in Taiwan’s 12-Year Curriculum.
Shih-Chao Yeh   +2 more
doaj   +1 more source

Sharing G. Evelyn Hutchinson's fabricational noise

open access: yesSign Systems Studies, 2000
One of the seminal constructs in 20th-century biosemiotics is G. Evelyn Hutchinson's 'niche'. This notion opened up and unpacked cartesian space and time to recognize self-organizing roles in open, dynamical systems — in n-dimensional hyperspace. Perhaps
Myrdene Anderson
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

UNDERSTANDING TEACHER USE OF INQUIRY: INVESTIGATING CATALYSTS AND BARRIERS

open access: yes, 2015
The purpose of this qualitative, multiple-case study was to investigate the catalysts and barriers related to implementing inquiry-based instruction in elementary school from the perspective of third, fourth, and fifth grade teachers.
Guertin, Susan
core  

Re-thinking missions ; a laymen's inquiry after one hundred years, by the Commission of appraisal, William Ernest Hocking, chairman. [PDF]

open access: yes, 1932
http://www.archive.org/details ...
Laymen's Foreign Missions Inquiry. Commission of Appraisal.   +1 more
core  

A case study on based on VR-based inquiry learning: Microcomputer assembly example

open access: yesSustainable Futures
The new curriculum standard issued by the Ministry of Education clearly advocates heuristic and inquiry-based teaching. Cultivating students' moral qualities and key abilities of independent inquiry and independent thinking are emphasized.
Liqiao Nong, Nan Gao, Xiaogui Zeng
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

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