Results 101 to 110 of about 1,932,624 (285)
OpenBiodiv: A Knowledge Graph for Literature-Extracted Linked Open Data in Biodiversity Science
Publications, 2019 Hundreds of years of biodiversity research have resulted in the accumulation of a substantial pool of communal knowledge; however, most of it is stored in silos isolated from each other, such as published articles or monographs.
Lyubomir Penev +6 more
doaj +1 more source
A linked data-driven & service-oriented architecture for sharing educational resources [PDF]
, 2011 The two fundamental aims of managing educational resources are to enable resources to be reusable and interoperable and to enable Web-scale sharing of resources across learning communities.
Dietze, Stefan +8 more
core
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Methodological InnovationsThere is limited methodological guidance on systematically integrating numerical-style responses with open-ended questions in online surveys. This paper addresses this gap by presenting the Scale, Choice and Insight (SCI) approach, which applies to both ...
David Meechan
doaj +1 more source
Towards linked open gene mutations data
BMC Bioinformatics, 2012 Background With the advent of high-throughput technologies, a great wealth of variation data is being produced. Such information may constitute the basis for correlation analyses between genotypes and phenotypes and, in the future, for personalized ...
Zappa Achille +2 more
doaj +1 more source
Open accessibility data interlinking
This paper presents the research of using Linked Open Data to enhance accessibility data for accessible travelling. Open accessibility data is the data related to the accessibility issues associated with geographical data, which could benefit people with
Ding, Chaohai, Wald, Mike, Wills, Gary
core
Für eine pan-europäische Lexikologie und Lexikographie mittels des Linked Open Data Frameworks
, 2015 A single abstract from the DHd-2015 Book of Abstracts.
Declerck, Thierry, Wandl-Vogt, Eveline
openaire +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Construction, Deployment, and Usage of the Human Reference Atlas Knowledge Graph
Scientific DataThe Human Reference Atlas (HRA) for the healthy, adult body is being developed by a team of international, interdisciplinary experts across 25+ consortia.
Andreas Bueckle +5 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source