Results 81 to 90 of about 1,932,624 (285)
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Citizen science for cuneiform studies
, 2012 This paper examines the potential applications of Citizen Science and Open Linked Data within a critical Web Science framework. Described here is a work-inprocess concerning an interdisciplinary, multiinstitutional project for the digitization ...
Dahl, Jacob +3 more
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In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Sematch: semantic entity search from knowledge graph [PDF]
, 2015 As an increasing amount of the knowledge graph is published as Linked Open Data, semantic entity search is required to develop new applications. However, the use of structured query languages such as SPARQL is challenging for non-skilled users who need ...
Iglesias Fernandez, Carlos Angel +1 more
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Linked Open Data: State-of-the-Art Mechanisms and Conceptual Framework
, 2020 Today, one of the state-of-the-art technologies that have shown its importance towards data integration and analysis is the linked open data (LOD) systems or applications. LOD constitute of machine-readable resources or mechanisms that are useful in describing data properties.
openaire +3 more sources
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
ISPRS International Journal of Geo-Information, 2017 There are many cases wherein services offered in geospatial sectors are integrated with other fields. In addition, services utilizing satellite data play important roles in daily life and in sectors such as environment and science.
Gooseon Yoon, Kwangseob Kim, Kiwon Lee
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Translating expressive ontology mappings into rewriting rules to implement query rewriting
, 2011 The increasing amount of structured RDF data published by the Linked Data community poses a great challenge when it comes to reconcile heterogeneous schemas adopted by data publishers.
Correndo, Gianluca, Shadbolt, Nigel
core