Results 61 to 70 of about 47,560,035 (275)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Environmental Spatio-temporal Ontology for the Linked Open Data Cloud [PDF]
, 2013 The rapid access of sensor technology provides both challenges and opportunities to authenticated spatiotemporal data. Authentication can be assured by developing related ontologies.
Ritaban Dutta +5 more
core +2 more sources
Interoperability Conflicts in Linked Open Statistical Data
Information, 2019 An important part of Open Data is of a statistical nature and describes economic and social indicators monitoring population size, inflation, trade, and employment.
Evangelos Kalampokis +2 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Personal Name Vocabularies as Linked Open Data: A Case Study of Jazz Artist Names [PDF]
, 2012 This paper describes the process of constructing a vocabulary of personal names of jazz artists in the form of Linked Open Data (LOD). Created as a name directory to support the development of the Linked Jazz project, it provides a case study that ...
Pattuelli, M. Cristina
core +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Mining Symptom and Disease Web Data with NLP and Open Linked Data [PDF]
, 2019 Machine Learning (ML) technologies in recent years are widely applied in various areas to assist knowledge gaining and decision-making on healthcare. However, there is no reliable dataset that contains semantic structured knowledge on symptom and disease
Yu, H., Hong Qing Yu, Yu, Hong Qing
core +1 more source
Linked Data and User Interaction
, 2015 This collection of research papers provides extensive information on deploying services, concepts, and approaches for using open linked data from libraries and other cultural heritage institutions.
IFLA Linked Data Special Interest Group
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source