Results 91 to 100 of about 168,982,903 (290)
Gong-kuang zidonghuaIn the single-bucket–truck process system of open-pit coal mines, coordinated operations between trucks and electric shovels often experience phenomena such as "trucks waiting for shovels" or "shovels waiting for trucks", leading to decreased ...
CHAI Senlin +5 more
doaj +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Coordination, Division of Labor, and Open Content Communities: Template Messages in Wiki-Based Collections. [PDF]
In this paper we investigate how in commons based peer production a large community of contributors coordinates its efforts towards the production of high quality open content. We carry out our empirical analysis at the level of articles and focus on the
Alessandro Rossi +3 more
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Journal of Open Innovation: Technology, Market and ComplexityOpen innovation ecosystems increasingly depend on collaboration between large enterprises and small and medium-sized enterprises (SMEs), yet such ecosystems remain vulnerable to demand volatility, cost instability, data fragmentation, and operational ...
SeongJeong Yoon, MinYeong Oh
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Transnational learning processes: European and Nordic experiences in the employment field [PDF]
This paper analyses and compares the transnational learning processes in the employment field in the European Union and among the Nordic countries. Based theoretically on a social constructivist model of learning and methodologically on a questionnaire ...
Nedergaard, Peter
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Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Who learns what? Policy learning and the open method of coordination [PDF]
, 2013 Paper prepared for the ESRC Seminar Series: 'Implementing the Lisbon Strategy, Policy Learning Inside and Outside the Open Method', held at the European Research Institute, University of Birmingham, Friday 26th November, 2004This paper provides a ...
Radaelli, Claudio M.
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