Results 71 to 80 of about 178,958,361 (288)
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
The Political Economy of Social Europe: The case of inclusion policies [PDF]
, 2003 EU governments have engaged in a coordinated effort to combat social exclusion. This is puzzling for empirical and theoretical reasons. The paper argues that integration of social inclusion policies can be explained by the political economy of domestic ...
Schelkle, Waltraud.
core
Open Method of Coordination in the European research policy
Acta Agraria Debreceniensis, 2007 Research, development and innovation (R+D) are of great importance nowadays as regards the competetiveness and economic growth of any given country. In the European Union the Lisbon Strategy considers R+D as a crutial means to enhance european competetiveness.
József Mikita, János Nagy
openaire +2 more sources
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
, 2014 Based on the findings of a large-scale, comparative research project, this book systematically assesses the institutional design and national influence of the Open Method of Coordination (OMC) on Social Inclusion and Social Protection, at the European ...
Barcevičius, E. +2 more
core +4 more sources
Las transformaciones de las fuentes de derecho del trabajo: Una aproximación
Cuadernos de Relaciones Laborales, 2008 The Spanish Labour Law system has been profoundly changed along the last three decades. These transformations have intensely and extendedly affected this system’s elements. The present article tries to offer a general perspective of those transformations,
Fernando Valdés Dal-ré
doaj
InorganicsX-ray absorption near-edge structure (XANES) spectra are employed to characterise the coordination numbers of metallic elements within materials. However, conventional XANES analysis methods frequently rely on preconceived assumptions regarding the ...
Jianan Gao +3 more
doaj +1 more source
Evolvement of Public Open Spaces in Historical Environments of Yerevan City
MATEC Web of Conferences, 2016 In this article the role of public open spaces in Yerevan city as well as their correct and literate organisation from an architectural and planning perspective are studied and evaluated.
Mamyan Zaruhi +2 more
doaj +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source