Results 61 to 70 of about 178,958,361 (288)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
The Open Method of Coordination (OMC) [PDF]
We interpret the Open Method of Coordination (OMC), recently adopted by the EU as a mode of governance in the area of social policy and other ¯elds, as an imitative learning dynamics of the type considered in evolutionary game theory.
Andreas Wagener, Ana B. Ania
core
DEVELOPMENTAL STAGES OF THE EDUCATIONAL STRATEGY OF THE EUROPEAN UNION
The article is dedicated to the analysis of the evolution of the educational strategy of EU in the process of its development aimed at the economic stability and security in the region.
Olena I. Lokshyna
doaj
Pelatihan Penyusunan Bahan Ajar Bahasa Indonesia bagi Guru Smp/Mts di Surakarta
This training has several goals, namely to open insights, and observers of Indonesian teachers about gender equality in everyday life, giving insight to analyze the value of inequality/ gender equality, and compile teaching materials Indonesian ...
Miftakhul Huda, Rahmah Purwahida
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Open Method of Coordination in the European Union: A Trojan Horse – But who is the rider?
There seems to be another spectre in Europe, this time it has a little bit of a hydra. The original name was «governance», seemingly a new born child, supposedly the successor of «governing». The parents seem to be a large E, standing for Europe and a
Peter Herrmann
doaj +2 more sources
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
A distribution network is transforming into multi-area distribution networks. Traditional iterative multi-area coordination methods protect the privacy of each area but face a high communication burden and convergence issues. To address these challenges,
Ling Luo +7 more
doaj +1 more source
Background The concept of single-port laparoscopic percutaneous extraperitoneal closure for the treatment of inguinal hernias repair in children has been practising recent years. The applicable instruments and skills are still evolving. In this study, we
Yuanhong Xiao
doaj +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source

