Results 101 to 110 of about 1,007,234 (319)
Molecular Oncology, EarlyView.Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard +12 more
wiley +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Research Data Cloud of Japan's Open Science Consortium [PDF]
Nongye tushu qingbao xuebao[Purpose/Significance] This paper focuses on the development process and service mechanisms of Japan's Research Data Cloud (RDC) system, a core national infrastructure coordinated by the Research Center for Open Science and Data Platform (RCOS).
CHENG Fan, GU Liping
doaj +1 more source
SMOC-Soft Open Method of Coordination from Prevalet
, 2011 Seven European Regional Governments, together with Earlall and universities and research centres, have undertaken to refine a first draft of a Joint Progress Report of Regions on Implementation of European Lifelong Learning Strategies in the perspective of the Europe 2020 Strategy.
openaire +1 more source
Hard and Soft Law in the European Union: The case of Social policy and the Open Method of Coordination [PDF]
The European integrative experiment rests on a dynamic equilibrium of intergovernmental and supranational features of the regulatory framework of the European Union.
Luca Barani
core
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
The open method of coordination and European integration
, 2008 Eight years ago, the Open Method of Coordination was codified as a mode of governance to implement the Lisbon strategy of the European Union which aims to turn the European economy into the most competitive and most dynamic knowledge-based economy in the world by 2010.
openaire +1 more source
Institutions, Governance and Economic Growth in the EU: is there a role for the Lisbon Strategy [PDF]
In order to ensure that the internal market delivers (growth, jobs) in the face of a changing market and technological environment (internal market liberalisation, globalisation, the knowledge-based economy) and to take advantage of the opportunities ...
Annette Bongardt, Francisco Torres
core
The European Employment Strategy. A New Form of Governance of Labour Markets in the European Union [PDF]
, 2007 The European Employment Strategy (EES) has been put in place in order to ensure the survival of the European Social Model in view of institutional change resulting from the introduction of the European Monetary System.
Biffl, Gudrun
core
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source