Results 61 to 70 of about 1,007,234 (319)
BMC Surgery, 2020 Background The concept of single-port laparoscopic percutaneous extraperitoneal closure for the treatment of inguinal hernias repair in children has been practising recent years. The applicable instruments and skills are still evolving. In this study, we
Yuanhong Xiao
doaj +1 more source
New Modes of Governance in Europe: Policy Making without Legislating? IHS Political Science Series: 2002, No. 81 [PDF]
, 2002 The article analyzes new modes of governance in Europe. Firstly, different types of new governance, the open coordination method and voluntary accords, and their individual elements are identified.
Héritier, Adrienne
core
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Failure of the Croatian Higher Education Reform
Center for Educational Policy Studies Journal, 2012 The authors analyse the reasons for Croatian higher education reform since 2003, as well as its consequences. The main proposition of the paper is that the implementation of the Bologna Process in Croatia has failed due to a fundamental misunderstanding
Zoran Kurelić, Siniša Rodin
doaj
A Service Supply Chain Synchronization Model [PDF]
مطالعات مدیریت راهبردی, 2021 Aim and Introduction. The issue of coordination identified as a key management issue in the supply chain. Service supply chain due to its different characteristics, and the products in the service supply chain are service-oriented, complex and more ...
Reza Jalil +2 more
doaj
Open Method of Coordination in the European research policy
Acta Agraria Debreceniensis, 2007 Research, development and innovation (R+D) are of great importance nowadays as regards the competetiveness and economic growth of any given country. In the European Union the Lisbon Strategy considers R+D as a crutial means to enhance european competetiveness.
József Mikita, János Nagy
openaire +2 more sources
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
The Open Method of Coordination on Health Care After the Lisbon Strategy II: Towards a Neoliberal Framing? [PDF]
, 2009 This paper undertakes a content analysis of the discourse on the Open Method of Coordination on Health Care (OMC/HC) in order to show how equity and solidarity are increasingly linked to optimisation and, as such, how neoliberalism increasingly frames ...
Flear, Mark
core +2 more sources