Results 71 to 80 of about 330,176 (256)

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

open access: yesFEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Does evaporation paradox exist in China? [PDF]

open access: yesHydrology and Earth System Sciences, 2009
One expected consequence of global warming is the increase in evaporation. However, lots of observations show that the rate of evaporation from open pans of water has been steadily decreasing all over the world in the past 50 years.
Z. T. Cong, D. W. Yang, G. H. Ni
doaj  

Micro-evolution of three Streptococcus species: selection, antigenic variation, and horizontal gene inflow

open access: yesBMC Evolutionary Biology, 2019
Background The genus Streptococcus comprises pathogens that strongly influence the health of humans and animals. Genome sequencing of multiple Streptococcus strains demonstrated high variability in gene content and order even in closely related strains ...
Pavel V. Shelyakin   +3 more
doaj   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Integration of Pan-Africanism and Regionalism in African Higher Education: A Cross-Disciplinary Study at the University of Johannesburg

open access: yesThe Thinker
This paper critically examines pedagogical ways to integrate Pan-Africanism across different disciplines at the University of Johannesburg such as Economics, Politics, Law, Medicine, Science, and Engineering.
Lisa Nyaude   +7 more
doaj   +1 more source

Reaction Spinning Titanium Dioxide Particle-Coated Carbon Fiber for Photoelectric Energy Conversion

open access: yesFibers, 2019
In this paper, a titanium dioxide particle coated carbon fiber was prepared by reaction spinning. Polyacrylonitrile (PAN) was used as the precursor to generate a continuous carbon nanofiber.
Leonardo Yuan   +7 more
doaj   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

Pan-genomic open reading frames: A potential supplement of single nucleotide polymorphisms in estimation of heritability and genomic prediction.

open access: yesPLoS Genetics, 2020
Pan-genomic open reading frames (ORFs) potentially carry protein-coding gene or coding variant information in a population. In this study, we suggest that pan-genomic ORFs are promising to be utilized in estimation of heritability and genomic prediction.
Zhengcao Li, Henner Simianer
doaj   +1 more source

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