Results 51 to 60 of about 16,682,348 (303)

A pan-Canadian measure of active living environments using open data

open access: yesHealth reports, 2019
The purpose of this paper is to describe the development of the Canadian Active Living Environments (Can-ALE) dataset: a Canada-wide set of four individual and four summary measures that characterize the favourability of active living environments in Canadian communities at the dissemination-area level.
Thomas, Hermann   +5 more
openaire   +2 more sources

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

PAN-00011099 - iron open socketed axe

open access: yes, 2020
This find is registered at Portable Antiquities of the Netherlands with number PAN ...
Portable Antiquities of the Netherlands, DataCurator
core   +1 more source

PAN-00052287 - small open bell Roman period

open access: yes, 2023
This find is registered at Portable Antiquities of the Netherlands with number PAN ...
Portable Antiquities of the Netherlands, DataCurator
core   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Journal Evaluation Model of the Pracownia Naukoznawstwa IHN PAN: Update of Journal Evaluation Rules and Journal Scoring in the History of Science in 2023

open access: yesStudia Historiae Scientiarum, 2023
The article presents: a) updating the rules for evaluating journals in the evaluation model developed in the Pracownia Naukoznawstwa IHN PAN (Science Studies and Science-of-Science Unit of the Institute for History of Science, Polish Academy of Sciences)
Michał Kokowski
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Genome Sequencing and Pan-Genome Analysis of 23 Corallococcus spp. Strains Reveal Unexpected Diversity, With Particular Plasticity of Predatory Gene Sets

open access: yesFrontiers in Microbiology, 2018
Corallococcus is an abundant genus of predatory soil myxobacteria, containing two species, C. coralloides (for which a genome sequence is available) and C. exiguus.
Paul G. Livingstone   +2 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

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