Results 61 to 70 of about 330,176 (256)

Astrocyte heterogeneity in brain metastases

Molecular Oncology, EarlyView.
Astrocytes emerge as pivotal regulators of metastatic colonization, survival, immune remodeling, and therapy response associated with an increasing heterogeneity that requires spatially and longitudinally resolved approaches to uncover regulatory programs and guide context‐specific therapies.
Carolina Hernández‐Oliver, Neibla Priego, Manuel Valiente   +2 more
wiley   +1 more source

Autonomous Cargo Transport System for an Unmanned Aerial Vehicle, using Visual Servoing [PDF]

Journal of Systemics, Cybernetics and Informatics, 2009
This paper presents the design and testing of a system for autonomous tracking, pickup, and delivery of cargo via an unmanned helicopter. The tracking system uses a visual servoing algorithm and is tested using open loop velocity control of a six degree ...
Noah Kuntz, Paul Oh
doaj  

ANALYSIS OF ASTEROID’S OBSERVATIONS IN OPEN PHOTOMETRIC DATABASES

Odessa Astronomical Publications, 2016
Today there are several open photometric databases containing important information for the study of the physical properties of asteroids. These databases are based on the results of various measurements of the different sets of objects.
N. Pomazan, N. Maigurova
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Pan American Bazaar: Consumer culture and popular participation in U.S. power (1939-1942)

Avances del Cesor, 2015
This article examines the brief rise of popular Pan Americanism in the United States, paying particular attention to the consumer culture that the movement awoke there.
Lisa Ubelaker
doaj  

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Pan-European open building footprints: analysis and comparison in selected countries [PDF]

The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences
This paper presents a comprehensive analysis of four non-governmental open building datasets available at the European Union (EU) level, namely OpenStreetMap (OSM), EUBUCCO, Digital Building Stock Model (DBSM) and Microsoft’s Global ML Building ...
M. Minghini, S. Thabit Gonzalez, L. Gabrielli   +2 more
doaj   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Acquisition of terrestrial life by human ancestors influenced by forest microclimate

Scientific Reports, 2017
Bipedalism, terrestriality and open habitat were thought to be linked to each other in the course of human evolution. However, recent paleontological evidence has revealed that early hominins evolved in a wooded, humid environment.
Hiroyuki Takemoto
doaj   +1 more source

Comparative Pan-Genome Analysis of Piscirickettsia salmonis Reveals Genomic Divergences within Genogroups

Frontiers in Cellular and Infection Microbiology, 2017
Piscirickettsia salmonis is the etiological agent of salmonid rickettsial septicemia, a disease that seriously affects the salmonid industry. Despite efforts to genomically characterize P.
Guillermo Nourdin-Galindo, Guillermo Nourdin-Galindo, Patricio Sánchez, Patricio Sánchez, Cristian F. Molina, Cristian F. Molina, Daniela A. Espinoza-Rojas, Daniela A. Espinoza-Rojas, Cristian Oliver, Cristian Oliver, Cristian Oliver, Pamela Ruiz, Pamela Ruiz, Luis Vargas-Chacoff, Juan G. Cárcamo, Juan G. Cárcamo, Jaime E. Figueroa, Jaime E. Figueroa, Marcos Mancilla, Vinicius Maracaja-Coutinho, Vinicius Maracaja-Coutinho, Vinicius Maracaja-Coutinho, Alejandro J. Yañez, Alejandro J. Yañez, Alejandro J. Yañez   +24 more
doaj   +1 more source