Results 111 to 120 of about 13,956 (306)

NADH‐Reductive Stress Induced by Dihydrolipoamide Dehydrogenase Activation Contributes to Cuproptosis

Advanced Science, EarlyView.
This study demonstrates a cuproptosis mechanism involving nicotinamide adenine dinucleotide (NADH)‐reductive stress in neural cells. Copper activates dihydrolipoamide dehydrogenase under mitochondrial pH, accumulating NADH. Copper also induces mitochondrial permeability transition pore opening, facilitating NADH translocation to the cytosol and ...
Si‐Yi Zhang, Xing‐Hua Ren, Cheng‐Hong Zhang, Zhan‐You Wang   +3 more
wiley   +1 more source

Cascade Therapy of Periodontitis via Sequential Release of Ribosome‐Targeting Antimicrobial Peptide and Irisin From a Multifunctional MOF‐Based System

Advanced Science, EarlyView.
This study presents a novel strategy for periodontitis treatment by co‐delivering a membrane‐ and ribosome‐targeting antimicrobial peptide GF and Irisin through a pH‐responsive metal‐organic framework. The system enables sequential release, providing rapid antibacterial action, anti‐inflammatory and antioxidative effects, as well as promoting bone ...
Yan Chen, Zheng Xu, Yunmo Xue, Shanshan Liu, Xiang Zhang, Jingyao Guo, Minhui Yao, Yue Liu, Xiaolin Lu, Jieshu Qian, Qian Ma   +10 more
wiley   +1 more source

Dorsal Raphe VIP Neurons Are Critical for Survival‐Oriented Vigilance

Advanced Science, EarlyView.
DRNVIP neurons in mice and primates are strategically positioned to influence the central extended amygdala via feedback loops. They regulate the excitability of PKC‐δ neurons in the ovBNST and CeA through glutamate release. Their ablation heightens activity in these regions, disrupts active‐phase sleep architecture, enhances risk assessment behaviors ...
Adriane Guillaumin, Emma Perrot, Thibault Dhellemmes, Laura Boi, Daniel De Castro Medeiros, Christelle Glangetas, Sylvie Dumas, Sandra Dovero, Nathalie Biendon, Elodie Ladeveze, Maëlle Hardel, Marc Landry, Erwan Bezard, Jérôme Baufreton, Gilberto Fisone, François Georges   +15 more
wiley   +1 more source

Examining Instructors’ Roles in Facilitating Students’ Learning Process in Pedagogical Information and Communication Technology Massive Open Online Course

, 2021
Ammar Bahadur Singh, Irina Engeness
openalex   +1 more source

Ethical and Frugal Approaches to Animal Experimentation in Bioelectronics and Neural Engineering—An Invertebrate Renaissance?

Advanced Electronic Materials, EarlyView.
Invertebrates are the classic neuroscience models and should make a comeback. Invertebrate organisms can be a more ethical and cost‐effective way to move bioelectronics research forward more rapidly. ABSTRACT The accelerating development of bioelectronic neural interfaces has brought increased attention to ethical considerations surrounding in vivo ...
Eric Daniel Głowacki
wiley   +1 more source

Electric and Temperature Field‐Modulated Periodic Repair of the Electrode/Electrolyte Interface toward Long Cycle Stability of Low‐Temperature Li‐Ion Batteries

Advanced Energy and Sustainability Research, EarlyView.
This study introduces a temperature‐electric field synergy strategy to enhance lithium‐ion battery performance at low temperatures. It reveals interfacial mechanisms: low temperatures cause deterioration, while room temperature aids stable interphase formation.
Zhenqiang Guo, Chengling Yang, Yu Fan, Yancai Zhang, Haolun Zou, Yukun Yan, Hongbin Zhang, Zhenhui Liu, Zinuo Chen, Sitong Peng, Ziyi Dang, Hengyi Li   +11 more
wiley   +1 more source

Patient Satisfaction With Medication Pricing in Community Pharmacy Settings: A Cross‐Sectional Study of Individuals With Comorbidities

AGING MEDICINE, EarlyView.
The majority of patients in Malaysia purchase medications at community pharmacies for simple medical conditions. One‐fourth of them are not satisfied with the pricing practices at these pharmacies. The majority rely on medical insurance to purchase routine medications.
Amelia Ravindran, Palanisamy Sivanandy, Sajesh Kalkandi Veettil, Priya Manirajan   +3 more
wiley   +1 more source

Exploring Personalized Learning and Open Education Pedagogy in Multilingual Learner Teacher Preparation

, 2023
Rhonda Bondie
openalex   +2 more sources

Behind the Scenes: Insights on Pedagogy during Implementation of an RbT Open Educational Resource [PDF]

, 2023
Susan Cox, Matthew Smithdeal, Michael Lee   +2 more
openalex   +1 more source

A Skills Gap Analysis of Farmer Directors of US Farmer Cooperatives

Agribusiness, EarlyView.
ABSTRACT Boards of directors are vital to firm performance and are an integral part of the decision‐making process of any business. Several studies have been conducted that observe corporate or nonprofit board characteristics, skills, and the board's connection to firm performance.
Jody S. Herchenbach, Brian C. Briggeman, Jason S. Bergtold, Aleksan Shanoyan, Sarah A. Low, Brandi Miller   +5 more
wiley   +1 more source