Results 121 to 130 of about 1,409,999 (372)
Small open reading frames and cellular stress responses
Molecular Omics, 2019 Increasing evidence suggests that some small open reading frame-encoded polypeptides (SEPs) function in prokaryotic and eukaryotic cellular stress responses.
Alexandra Khitun +2 more
openaire +4 more sources
Characterization of Full Length Sequence of JJ3 Isolated From Shade Tolerant Soybean [PDF]
, 2008 The aim of this study was to characterize full length sequence of JJ3 isolated from shade tolerant soybean. The characterization of full length sequence involved analyses of structure of full length sequence, open reading frame (ORF) or coding sequence ...
Khumaida, N. (Nurul) +2 more
core
ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma
Molecular Oncology, EarlyView.In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In
Daniel K. C. Lee +9 more
wiley +1 more source
Neoplasia: An International Journal for Oncology Research, 2006 We characterized the molecular genetic consequences of a balanced chromosome translocation t(8;22)(p21; q12), which occurred as the sole cytogenetic aberration in short-term cultured cells from an intrathoracic mature teratoma in a 15-year-old girl ...
Yuesheng Jin +3 more
doaj +1 more source
A natural uORF variant confers phosphorus acquisition diversity in soybean
Nature Communications, 2022 Improving phosphorus (P) acquisition efficiency is important for sustainable agriculture. Here, the authors report a natural variation in an upstream open reading frame of a SEC12-like gene GmPHF1 is crucial for protein abundance and spatial distribution
Zilong Guo +15 more
doaj +1 more source
PLoS Pathogens, 2011 Small RNA viruses have evolved many mechanisms to increase the capacity of their short genomes. Here we describe the identification and characterization of a novel open reading frame (ORF4) encoded by the murine norovirus (MNV) subgenomic RNA, in an ...
Nora McFadden +10 more
semanticscholar +1 more source
Hundreds of putatively functional small open reading frames in Drosophila [PDF]
Genome Biology, 2011 Abstract Background The relationship between DNA sequence and encoded information is still an unsolved puzzle. The number of protein-coding genes in higher eukaryotes identified by genome projects is lower than was expected, while a considerable amount of putatively non-coding transcription has been ...
Vini Pereira +4 more
openaire +4 more sources
The role of circular RNAs in regulating cytokine signaling in cancer
FEBS Open Bio, EarlyView.Cytokines present in the tumor microenvironment fuel cancer development. Aberrant expression of circRNAs contributes to cancer progression. Cytokines are involved in regulating circRNA biogenesis. Furthermore, aberrantly expressed circRNAs regulate the expression of ligands, receptors, and downstream effectors involved in cytokine signaling to promote ...
Vandana Joshi +4 more
wiley +1 more source
Dual expression recombinase based (DERB) single vector system for high throughput screening and verification of protein interactions in living cells [PDF]
, 2008 Identification of novel protein interactions and their mediators is fundamental in understanding cellular processes and is necessary for protein-targeted therapy.
Jehonathan Pinthus +2 more
core +2 more sources
FEBS Open Bio, EarlyView.This study presents a novel approach to teaching Python and bioinformatics using team‐based learning and cloud‐hosted notebooks. By integrating interactive coding into biomedical education, the method improves accessibility, student engagement, and confidence—especially for those without a computing background.
Nuno S. Osório, Leonardo D. Garma
wiley +1 more source