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Advanced Materials Technologies, EarlyView.This review highlights advances in printing with nano‐ and microparticulate diamond for applications such as sensors, thermal management, machining tools, and biointerfaces. By covering screen, inkjet, microcontact, and 3D printing techniques, it outlines how diamond particles can be integrated into composite materials and functional devices, while ...
Simona Baluchová +1 more
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The Definition of Open Reading Frame Revisited.
Trends in Genetics, 2018The term open reading frame (ORF) is of central importance to gene finding. Surprisingly, at least three definitions are in use. We discuss several molecular biological and bioinformatics aspects, and we recommend using the definition in which an ORF is bounded by stop codons.
Patricia Sieber, M. Platzer, S. Schuster
semanticscholar +4 more sources
Proteomics, 2021
The recent discovery of alternative open reading frames creates a need for suitable analytical approaches to verify their translation and to characterize the corresponding gene products at the molecular level.
Liam Cassidy +5 more
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The recent discovery of alternative open reading frames creates a need for suitable analytical approaches to verify their translation and to characterize the corresponding gene products at the molecular level.
Liam Cassidy +5 more
semanticscholar +1 more source
Coupling of Open Reading Frames by Translational Bypassing
Annual Review of Biochemistry, 2000▪ Abstract Translational bypassing joins the information found within two disparate open reading frames into a single polypeptide chain. The underlying mechanism centers on the decoding properties of peptidyl-transfer RNA (tRNA) and involves three stages: take-off, scanning, and landing.
John F. Atkins +2 more
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[8] Searching for clones with open reading frames
1987Publisher Summary This chapter has devised a simple strategy to quickly locate and express open reading frames. Using this approach, it is possible to identify protein coding regions without any extensive information about the products. One of the distinguishing features of deoxyribo nucleic acid (DNA) in protein-coding regions is the presence of at ...
Mark R. Gray +3 more
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Bioprospecting Open Reading Frames for Peptide Effectors
2013Recent successes in the development of small-molecule antagonists of protein-protein interactions designed based on co-crystal structures of peptides bound to their biological targets confirm that short peptides derived from interacting proteins can be high-value ligands for pharmacologic validation of targets and for identification of druggable sites.
Charles P. Scott, Ling Xiong
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Inferring genes from open reading frames
Computers & Chemistry, 1994One expects that in DNA without protein coding function, stop codons (which constitute three of the 64 possible codons) should occur frequently in all reading frames, and that a long open reading frame (ORF) can be interpreted as a sign for the existence of a gene.
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Module 5: The Need for an Open Reading Frame
2020In this module, students will learn to identify the open reading frames for a given gene, and define the phases of the splice donor and acceptor sites.
Leocadia V. Paliulis +2 more
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Regulation of plant translation by upstream open reading frames
Plant Science, 2014We review the evidence that upstream open reading frames (uORFs) function as RNA sequence elements for post-transcriptional control of gene expression, specifically translation. uORFs are highly abundant in the genomes of angiosperms. Their negative effect on translation is often attenuated by ribosomal translation reinitiation, a process whose ...
Albrecht G. von Arnim +2 more
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