Results 101 to 110 of about 780,027 (226)
Thousands of novel translated open reading frames in humans inferred by ribosome footprint profiling
bioRxiv, 2015 Accurate annotation of protein coding regions is essential for understanding how genetic information is translated into biological functions. Here we describe riboHMM, a new method that uses ribosome footprint data along with gene expression and sequence
Anil Raj +8 more
semanticscholar +1 more source
C11ORF30 (chromosome 11 open reading frame 30) [PDF]
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011 Review on C11ORF30 (chromosome 11 open reading frame 30), with data on DNA, on the protein encoded, and where the gene is implicated.
JL Huret, S Senon
openaire +1 more source
Genome Research, 2015 Mammalian gene expression displays widespread circadian oscillations. Rhythmic transcription underlies the core clock mechanism, but it cannot explain numerous observations made at the level of protein rhythmicity.
Peggy Janich +4 more
semanticscholar +1 more source
Gene expression regulation by upstream open reading frames in rare diseases [PDF]
, 2017 Upstream open reading frames (uORFs) constitute a class of cis-acting elements that regulate translation initiation. Mutations or polymorphisms that alter, create or disrupt a uORF have been widely associated with several human disorders, including ...
Fernandes, Rafael +2 more
core
Hepatitis E virus mixed infection in immunocompetent patient [PDF]
, 2013 We detected 2 hepatitis E virus (HEV) strains in an acutely infected immunocompetent patient. Two populations of genotype 3 virus were observed in the hypervariable regions and open reading frames 2 and 3, indicating multiple infection with hepatitis E ...
Abe +20 more
core +2 more sources
Phage ϕC2 mediates transduction of Tn6215, encoding erythromycin resistance, between Clostridium difficile strains [PDF]
, 2013 UNLABELLED: In this work, we show that Clostridium difficile phage ϕC2 transduces erm(B), which confers erythromycin resistance, from a donor to a recipient strain at a frequency of 10(-6) per PFU.
Chang, Barbara J +5 more
core +3 more sources
Cell Reports, 2014 High-throughput gene expression analysis has revealed a plethora of previously undetected transcripts in eukaryotic cells. In this study, we investigate >1,100 unannotated transcripts in yeast predicted to lack protein-coding capacity.
Jenna E. Smith +7 more
semanticscholar +1 more source
Gene Designer: a synthetic biology tool for constructing artificial DNA segments [PDF]
, 2006 Background Direct synthesis of genes is rapidly becoming the most efficient way to make functional genetic constructs and enables applications such as codon optimization, RNAi resistant genes and protein engineering.
Minshull Jeremy +4 more
core +2 more sources
Conservation of uORF repressiveness and sequence features in mouse, human and zebrafish
Nature Communications, 2016 Upstream open reading frames (uORFs) can repress gene expression. Here, Guo-Liang Chew and colleagues use bioinformatics approaches to show that conservation of uORF-mediated translational repression is mediated by sequence features in human, mouse and ...
Guo-Liang Chew +2 more
doaj +1 more source
Bad Phages in Good Bacteria: Role of the Mysterious orf63 of λ and Shiga Toxin-Converting 824B Bacteriophages [PDF]
, 2017 Lambdoid bacteriophages form a group of viruses that shares a common schema of genome organization and lifecycle. Some of them can play crucial roles in creating the pathogenic profiles of Escherichia coli strains. For example, Shiga toxin-producing E.
Bloch, Sylwia +10 more
core +2 more sources