Results 101 to 110 of about 16,981,451 (257)
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
, 2004 Title from screen 1, right panel (viewed Oct. 8, 2004).; "Auditor of State, Betty Montgomery."; Electronic text (pdf, 2 p.).; Harvested from the web on 10/8 ...
Ohio. Open Government Unit
core
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Laparoscopic vs. open inguinal hernia repair outcomes in patients aged 65 years and older
Frontiers in SurgeryBackgroundInguinal hernia affects approximately 27% of men and 3% of women, with prevalence rising markedly after age 65 due to weakened abdominal walls and comorbidities such as chronic obstructive pulmonary disease and benign prostatic hyperplasia ...
Abdulkarem Al-Sharabi +13 more
doaj +1 more source
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
FEBS Letters, EarlyView.Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
Creating open educational resources
, 2010 Are you interested in creating your own open educational resources? This unit will help you to write a learning unit and provide you with links to various resources for open-learning materials.
Open University
core
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Frontiers in NutritionIntroductionAbdominal aortic aneurysms (AAA) are a potentially fatal vascular condition defined by an aortic diameter exceeding 3.0 cm or demonstrating a ≥50% increase in the normal diameter.
Eliza Russu +22 more
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Activated coagulation during open and endovascular abdominal aortic aneurysm repair
, 2006 OBJECTIVE: The study was conducted to determine activation of coagulation in patients undergoing open and endovascular infrarenal abdominal aortic aneurysm repair (EVAR).
Englberger, Lars +8 more
core +1 more source