Results 41 to 50 of about 5,322,488 (334)
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
This study explores the speed adjustment characteristics of the adaptive control of estimated single-layer Bi-channel neural networks (NNs) for Variable Reluctance Motor (VRM) drives.
Hamad Alharkan
doaj +1 more source
Capacitance Control on the Wire Production Line
The paper presents technical implementation of the electricalcapacitive method to perform in-process measurement of the capacitance per unit length of a single-core electric wire. The design of the electrocapacitive measuring transducer is proposed.
Goldshtein Alexander+2 more
doaj +1 more source
For effect of CE 853/04 Regulation slaughterhouses authorized as low-capacity establishments under 91/497/CEE directive and 286/94 Decree, had to obtain the approval by 31/12/2009 to continue operating.
E. Paladino+3 more
doaj +1 more source
Asymmetric targeting of corporate cash holdings and financial constraints in Pakistani firms [PDF]
Purpose – The purpose of this paper is to investigate the asymmetric adjustment of cash holdings in Pakistani firms for above and below target firms. Design/methodology/approach – The study employs generalized method of moments (GMM) to investigate the ...
Ghulam Ayehsa Siddiqua+2 more
doaj +1 more source
A Ku-Band Foldable Reflectarray Based on a Maltese-Cross Microstrip Element
Introduction. Reflectarrays have a number of design and functional advantages over their closest analogue - reflector antennas (RA). Although microstrip elements are the most preferred reflectarray elements, single-layer microstrip elements do not allow ...
S. V. Polenga+5 more
doaj +1 more source
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro+2 more
wiley +1 more source
Intelligent adjustment for power system operation mode based on deep reinforcement learning
Power flow adjustment is a sequential decision problem. The operator makes decisions to ensure that the power flow meets the system's operational constraints, thereby obtaining a typical operating mode power flow.
Wei Hu+5 more
doaj +1 more source
ESTIMATION OF THE RELATION BETWEEN WEIBULL SEA CLUTTER AND THE CA-CFAR SCALE FACTOR
When radars operate in coastal or offshore environments, an undesired signal known as clutter appears as background in the measurements. The CA-CFAR detector is the classic solution for the detection of targets inside clutter, typically using a fixed ...
José Raúl Machado Fernández
doaj +1 more source