Results 41 to 50 of about 5,322,488 (334)

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

Estimating Single Layer Bi-Channel Neural Networks Architecture for Speed Control of Variable Reluctance Motors

open access: yesEnergies
This study explores the speed adjustment characteristics of the adaptive control of estimated single-layer Bi-channel neural networks (NNs) for Variable Reluctance Motor (VRM) drives.
Hamad Alharkan
doaj   +1 more source

Capacitance Control on the Wire Production Line

open access: yesMATEC Web of Conferences, 2016
The paper presents technical implementation of the electricalcapacitive method to perform in-process measurement of the capacitance per unit length of a single-core electric wire. The design of the electrocapacitive measuring transducer is proposed.
Goldshtein Alexander   +2 more
doaj   +1 more source

LOW- CAPACITY SLAUGHTERHOUSES STRUCTURAL ADJUSTMENT FOR THE APPROVAL PROVIDED FOR BY 853/2004 REGULATION. EXPERIENCES OF THE LOCAL SANITARY AUTHORITY OF THE PROVINCE OF BERGAMO

open access: yesItalian Journal of Food Safety, 2011
For effect of CE 853/04 Regulation slaughterhouses authorized as low-capacity establishments under 91/497/CEE directive and 286/94 Decree, had to obtain the approval by 31/12/2009 to continue operating.
E. Paladino   +3 more
doaj   +1 more source

Asymmetric targeting of corporate cash holdings and financial constraints in Pakistani firms [PDF]

open access: yesJournal of Asian Business and Economic Studies, 2019
Purpose – The purpose of this paper is to investigate the asymmetric adjustment of cash holdings in Pakistani firms for above and below target firms. Design/methodology/approach – The study employs generalized method of moments (GMM) to investigate the ...
Ghulam Ayehsa Siddiqua   +2 more
doaj   +1 more source

A Ku-Band Foldable Reflectarray Based on a Maltese-Cross Microstrip Element

open access: yesИзвестия высших учебных заведений России: Радиоэлектроника, 2021
Introduction. Reflectarrays have a number of design and functional advantages over their closest analogue - reflector antennas (RA). Although microstrip elements are the most preferred reflectarray elements, single-layer microstrip elements do not allow ...
S. V. Polenga   +5 more
doaj   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Intelligent adjustment for power system operation mode based on deep reinforcement learning

open access: yesiEnergy
Power flow adjustment is a sequential decision problem. The operator makes decisions to ensure that the power flow meets the system's operational constraints, thereby obtaining a typical operating mode power flow.
Wei Hu   +5 more
doaj   +1 more source

ESTIMATION OF THE RELATION BETWEEN WEIBULL SEA CLUTTER AND THE CA-CFAR SCALE FACTOR

open access: yesIngeniería, 2015
When radars operate in coastal or offshore environments, an undesired signal known as clutter appears as background in the measurements. The CA-CFAR detector is the classic solution for the detection of targets inside clutter, typically using a fixed ...
José Raúl Machado Fernández
doaj   +1 more source

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