Results 61 to 70 of about 300,033 (304)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Experimental relationships between operating speeds of successive road design elements in two-lane rural highways

open access: yesTransport, 2017
Speed has been identified for a long time as a key risk factor in road traffic. Inappropriate speeds contribute to a relevant part of road crashes, and then to the mortality and disabilities resulting from them.
Laura Eboli   +3 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Adjustable speed operation of a hydropower plant associated to an irrigation reservoir [PDF]

open access: yes, 2008
This paper deals with the issue of adjustable speed operation (ASO) of hydropower plants. The main idea of this technique is to allow the turbine speed to change in accordance with hydraulic conditions, thus improving the overall unit efficiency. General
Wilhelmi Ayza, José-Román   +2 more
core   +2 more sources

Speed Analyses of Intersections Reconstructed into Roundabouts: A Case Study from Rijeka, Croatia

open access: yesInfrastructures
The reconstruction of a standard at-grade intersection into a roundabout is very often motivated by the need to improve traffic safety, and the effects are usually monitored through before–after analyses based on traffic accidents.
Sanja Šurdonja   +2 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

A Unified Mathematical Model for High Speed Hybrid (Air and Water-borne) Vehicles. [PDF]

open access: yes, 2007
During the last two decades, the interest in civil and military high speed marine vehicles has lead to several new configurations. Some of them exploit a combination of aerodynamic and hydrodynamic forces to sustain part of the weight of the craft ...
Patel, Minoo H.   +2 more
core  

The (in)efficiency of trams and buses in Brussels: a fine geographical analysis

open access: yesBrussels Studies, 2008
At a time when mobility in Brussels is becoming increasingly critical from the standpoints of the environment and efficiency, this article gives a detailed and exhaustive analysis of the geography of traffic conditions affecting the trams and buses of ...
Xavier Courtois, Frédéric Dobruszkes
doaj   +1 more source

Speed limit operators for oscillating speed functions

open access: yesOsaka Journal of Mathematics, 1994
Let \(\mathcal F\) denote the class of step functions on the real line \(R\), so that, in particular, elements of \(\mathcal F\) are expressible as linear sums of functions of the form \(f_0\), where \(f_0(t)=a\sum^n_{j=1}\psi_{(a,b)}(t)\), \(\psi_{(a,b)}(t)=1\) if \(a0\}\) is a semigroup of operators. The results of this paper involve the construction
Fernow, Berndt, Krengel, Ulrich
openaire   +4 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

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