Results 111 to 120 of about 1,235,898 (307)
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
BadDomains: Early Detection of Phishing Domains Registration
SensorsPhishing attacks often rely on impersonating a legitimate entity, such as a well-known company or a bank, with the intent to deceive individuals. A common tactic used by cybercriminals to conduct such an attack is to register a specific domain to host a ...
Karolina Seweryn +2 more
doaj +1 more source
New safety model for the commercial human spaceflight industry [PDF]
, 2011 The aviation and space domains have safety guidelines and recommended practices for Design Organisations (DOs) and Operators alike. In terms of Aerospace DOs there are certification criteria to meet and to demonstrate compliance there are Advisory ...
Bond, S.J., Maropoulos, P., Quinn, A.
core
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
STPA analysis for safe operation of maritime autonomous surface ship under degradation state
Frontiers in Marine ScienceAs Maritime Autonomous Surface Ships (MASS) move toward commercialization, ensuring operational safety under degraded states has emerged as a critical challenge.
Hyeri Park, Jeongmin Kim
doaj +1 more source
CLEAR: Communications Link Expert Assistance Resource [PDF]
Communications Link Expert Assistance Resource (CLEAR) is a real time, fault diagnosis expert system for the Cosmic Background Explorer (COBE) Mission Operations Room (MOR).
Hughes, Peter M., Hull, Larry G.
core +1 more source
Comment: Classifier Technology and the Illusion of Progress--Credit Scoring
, 2006 Comment on Classifier Technology and the Illusion of Progress--Credit Scoring [math.ST/0606441]Comment: Published at http://dx.doi.org/10.1214/088342306000000051 in the Statistical Science (http://www.imstat.org/sts/) by the Institute of Mathematical
Gayler, Ross W.
core +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source