Results 171 to 180 of about 1,235,898 (307)

Low-Power Embedded Sensor Node for Real-Time Environmental Monitoring with On-Board Machine-Learning Inference. [PDF]

Sensors (Basel)
Reis MJCS.
europepmc   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Analysis of Off-Design Performance and Thermal-Fluid-Structural Coupling Characteristics of an Adjustable Air Ejector. [PDF]

Materials (Basel)
Zhang Y, Yan L, Zhang J, Ma S, Guo W.
europepmc   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Health impact assessment of decentralization of Emergency Medical Services: a case study in Chonburi Province, Thailand. [PDF]

Sci Rep
Jaidee PH, Bundittayanurak A, Jindasawat R, Wongdontree S, Sangjun S, Patipat P, Yingklang M.   +6 more
europepmc   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

SIAP: Synthetic dataset for maritime vessel risk profiling and illegal activity prediction. [PDF]

Data Brief
Karamolegkos S, Dourvas NΙ, Episkopos N, Pikounis K, Michail E, Ioannidis K, Vrochidis S.   +6 more
europepmc   +1 more source

Ruling the Operational Boundaries: A Survey on Operational Design Domains of Autonomous Driving Systems

IFAC-PapersOnLine, 2023
Marcel Aguirre Mehlhorn, Andreas Richter, Yuri A.W. Shardt   +2 more
openaire   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Kriging to Kolmogorov-Arnold Network model accelerated discovery of oxygen control strategy in lead-based fast reactors. [PDF]

Nat Commun
Wang S, Chen J, Liu X, Zhang T, Chai X, Lu Q, Shen D, He H.   +7 more
europepmc   +1 more source