How Can Operational Research Help to Eliminate Tuberculosis in the Asia Pacific Region?
Broad multi-sectoral action is required to end the tuberculosis (TB) epidemic by 2030 and this includes National TB Programmes (NTPs) fully delivering on quality-assured diagnostic, treatment and preventive services.
Anthony D. Harries +6 more
doaj +1 more source
Anisakis infection in allis shad, Alosa alosa (Linnaeus, 1758), and twaite shad, Alosa fallax (Lacépède, 1803), from Western Iberian Peninsula Rivers : zoonotic and ecological implications [PDF]
Acknowledgments The authors would like to thank M. N. Cueto and J.M. Antonio (ECOBIOMAR) for their excellent technical support and also Rodrigo López for making the map of the study area.
Antunes, C. +7 more
core +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Balancing Financial Viability and User Affordability: An Assessment of Six WASH Service Delivery Models [PDF]
This Topic Brief presents assessments of the financial performance of six WSUP-supported WASH service delivery models in Bangladesh, Madagascar, Mozambique and Zambia.
Baghi Baghirathan, Sam Drabble
core
Mechanisms of parasite‐mediated disruption of brain vessels
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
OPERATIONAL PROGRAMME - DEVELOPMENT OF EASTERN POLAND, 2007 – 2013. DEVELOPMENT OPPORTUNITIES OF LUBLIN VOIVODESHIP AND THE INSTRUMENT OF REGIONAL CONVERGENCE [PDF]
The entire European Union is made up of the elements characterized by, among others, different level of economic development. So far, a measure of the level of the development is Gross Domestic Product per capita.
Magdalena Czerwiñska
core
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
ISSUES THAT CONTRIBUTE TO MAINTAINING A LOW LEVEL OF EMPLOYMENT AND WORK IN ROMANIA COVERED BY THE OPERATIONAL PROGRAMME HUMAN CAPITA [PDF]
Ensuring the availability of a workforce that meets the growing needs of the business environment is one of the important factors for promoting competitive growth and to stimulate economic activity in the less-developed areas, to contribute to the ...
BUȘAN GABRIELA , ECOBICI NICOLAE
doaj
FINANCIAL INDICATORS FOR THE IMPLEMENTATION OF AN EUROPEAN FUNDED INVESTMENT PROJECT UNDER SOP IEC PROGRAMME – CASE STUDY OF A ROMANIAN SME [PDF]
The European Integration came with new challenges for the Romanian enterprises especially for the SMEs, the opportunities arising from operating on the European Single Market and the possibility for accession of European Regional Development Funds.
Droj Laurentiu
core

