Results 121 to 130 of about 78,638 (313)
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
The Evaluation of the Operational Programme Environment in the Zlín Region 2007 - 2013
, 2014 Téma této diplomové práce je "Evaluace Operačního programu Životní prostředí ve Zlínském kraji v programovém období 2007-2013". Cílem práce je poskytnout přehled o kohezní politice EU a vyhodnotit implementaci Operačního programu Životní prostředí ve ...
Kučerová, Renáta
core
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
The operational programme environment and its usage
, 2010 Diplomová práce je zaměřena na popis postupů spojených s přípravou a uplatněním žádosti o finanční podporu z Fondů EU. Cílem práce je poskytnout zájemcům přehledný a srozumitelný materiál usnadňující orientaci v dané problematice.This thesis deals with ...
Kinkor, Pavel
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Evaluation of the impact of public support from the point of convergence criterion
Littera Scripta, 2016 The article deals with the ex post evaluation of the impact of drawing funds from operational programmes to achieve convergence in the field of tourism after the Czech Republic became a member of the EU.
Lucie Sobotková, Martin Sobotka
doaj
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Using an Operational Programme to Manage Changes During Modelling
, 2015 Käesoleva lõputöö, „Rakenduskava kasutamine projekteerimise juhtimiseks”, eesmärgiks oli selgitada rakenduskava vajalikkust projekteerimise täpsustuste juhtimisel ning kirjeldada rakenduskava olulisemaid punkte. Lõputöö koostamisel tugineti eelkõige veel
Orumets, Karl
core
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Entrepreneurship in Tourism and Financing through the Regional Operational Programme
Amfiteatru Economic, 2015 The European Structural Funds have stood, as early as their very establishment back 1957, for a tool of economic and social harmonization of the Member States of the European Union.
Mihaela Ana Pădurean +2 more
doaj
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source