Results 221 to 230 of about 78,638 (313)

Identifying barriers and policy priorities for rare disease research in underrepresented European countries. [PDF]

Eur J Public Health
Lace B, Inashkina I, Dan D, Weinman A, Adam P, Kvlividze O, Tumiene B, Isidro A, Pereira CA, Teixeira G, Crowley RK, ERDERA UC Stakeholder Panel .   +11 more
europepmc   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source

Important entomological events in the history of onchocerciasis ('river blindness'). [PDF]

Int Health
Mackenzie CD, Post RJ, Boakye DA.
europepmc   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

Factors affecting implementation of hospital inpatient-level care at home: a qualitative study of virtual wards in North West England. [PDF]

BMJ Open
Bradley F, Howells K, Gasteiger N, Sanders C, Blakeman T, Dowding D.   +5 more
europepmc   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Climate change and malaria control in Africa: country experiences and strategic responses. [PDF]

Malar J
Yahouedo AG, Merle CS, Diallo I, Ndiop M, Muhire A, Mukashema C, Mutabazi A, Hakizimana E, Muteba C, Kaseba AN, Tanoh MA, Aimain AS, Coulibaly KA, Razanakotomalala V, Diar MSI, Djaskano MI, Kodindo I, Ayala D, Caminade C, Diouf I, de Chevigny T, Ngou O, Pothin E, Girond F, Tchouatieu AM, Fleutelot E, Noseda V, Deuve JL.   +27 more
europepmc   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

What is the feasibility and acceptability of stool sampling and testing for childhood tuberculosis diagnosis? A qualitative study in The Gambia. [PDF]

BMJ Open
Owusu SA, Edem VF, Nkereuwem E, Danso M, Boakarie M, Koita SW, Kandeh S, Jallow M, Baldeh T, Gomez M, Busza J, Togun TO.   +11 more
europepmc   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source