Results 231 to 240 of about 2,387,864 (261)

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

FEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura, Kengo Furuichi, Hiromitsu Akamatsu, Naoki Yamamoto, Sako Keisuke, Akihiko Koshino, Taichiro Minami, Megumi Oshima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Kenta Takahashi, Minako Yamamura, Shin‐ichi Horike, Takiko Daikoku, Kenichi Harada, Yohei Shinmyo, Hiroshi Kawasaki, Takashi Wada, Yasunori Iwata   +19 more
wiley   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source

Acute internal medicine as the engine room of the modern hospital: The Midland Metropolitan University Hospital blueprint. [PDF]

Future Healthc J
Clare S, Ho J, Barlow R.
europepmc   +1 more source

Implementation strategies for integrating non-communicable disease care into primary healthcare settings in sub-Saharan Africa: A systematic review. [PDF]

PLOS Glob Public Health
Amu H, Brinsley TY, Oppong J.
europepmc   +1 more source

Digital tools not enough; quality control-linked incentives are needed for tuberculosis active case finding. [PDF]

Public Health Action
Abdullah H, Shewade HD, Manickam P, Gupta K, Ambiya MS, Dhakad RS, Sharma K, Nag S, Shahnawaz M, Nagar R.   +9 more
europepmc   +1 more source

Sustaining the Elimination of Visceral Leishmaniasis: A Secondary Data Analysis of the National Kala-Azar Elimination Programme in Malda District, West Bengal, India (2018-2022). [PDF]

Cureus
Halder T, Debnath P, Pal J, Ghosh M.
europepmc   +1 more source

A Roadmap for National Diabetic Retinopathy Screening in Croatia: Integrating European Evidence, Telemedicine, and AI. [PDF]

Medicina (Kaunas)
Babić T, Tomić M, Vukojević N, Dumić-Čule I, Jandroković S, Mance TČ.   +5 more
europepmc   +1 more source