Results 161 to 170 of about 2,531,355 (284)

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

A Qualitative, multitiered operational research model for teenagers and young adults with autism: Actionable insights from an Indian context. [PDF]

Indian J Psychiatry
Chandran S, Shetty H, Mathew A, Rao V, Mysore A.   +4 more
europepmc   +1 more source

Introduction to the special issue on the role of operational research in future epidemics/ pandemics. [PDF]

Eur J Oper Res, 2023
Farahani RZ, Ruiz R, Van Wassenhove LN.
europepmc   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Improved Utilisation and Quality of Blood Culture Services Following Operational Research in a Tertiary Hospital in Ghana. [PDF]

Trop Med Infect Dis
Sewornu R, Boakye-Yiadom E, Ativi E, Kwadzokpui PK, Senahey B, Owusu H, Thekkur P, Kumar AMV, Dodoo CC.   +8 more
europepmc   +1 more source

Capacity building in operational research on obstetric fistula: Experience in the Democratic Republic of Congo, 2017-2021. [PDF]

Int J Gynaecol Obstet, 2023
Delamou A, Tripathi V, Camara BS, Sidibe S, Grovogui FM, Kolie D, Bouedouno P, Kourouma K, Banze DF, Mafu MM.   +9 more
europepmc   +1 more source

Orbital operations study Third semiannual progress report, 15 May - 14 Nov. 1965 [PDF]

Automatic information forms of orbital data, data recorder fabrication, data output buffer development, and operational engineering research in orbital operations control ...

core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Is household contact investigation a missing link for tuberculosis care in Chhattisgarh, India?-Operational research using programmatic data. [PDF]

PLOS Glob Public Health
Malik C, Gupta V, Shringarpure K, Gupte HA, Shewade HD, Keshri VR, Tripathi N, Sonwani K, Kalkonde Y, Jain Y.   +9 more
europepmc   +1 more source

Prioritization of operational research questions on COVID-19 vaccination in the African Region. [PDF]

Pan Afr Med J, 2022
Masresha B, Bwaka A, Mihigo R.
europepmc   +1 more source