Results 111 to 120 of about 1,139,169 (382)
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
Evaluation of functional outcome and patient satisfaction after arthroscopic elbow arthrolysis [PDF]
, 2008 Arthroscopic arthrolysis is indicated for stiffness and pain caused by intrinsic stiffness and early arthritis of the elbow joint. Previous studies have demonstrated the benefits in relieving pain and improving motion, but none have reported the ...
Funk, L, Somanchi, BV
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Recommendations for the management of MPS IVA: systematic evidence- and consensus-based guidance. [PDF]
, 2019 IntroductionMucopolysaccharidosis (MPS) IVA or Morquio A syndrome is an autosomal recessive lysosomal storage disorder (LSD) caused by deficiency of the N-acetylgalactosamine-6-sulfatase (GALNS) enzyme, which impairs lysosomal degradation of keratan ...
Akyol, Mehmet Umut +30 more
core +2 more sources
Reintervenciones quirúrgicas en el servicio de cirugía del hospital "Aleida Fernández Chardiet"
Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2016 Fundamento: las relaparotomías pueden ser programadas o a demanda; esta última se decide acorde a la evolución posoperatoria del enfermo, el juicio clínico del especialista en cirugía y el equipo médico de apoyo.Objetivo: caracterizar las ...
Victor Manuel Sierra Alfonso
doaj
International Brazilian Journal of UrologyIntroduction To evaluate the safety and efficacy of a novel penile circumcision suturing devices PCSD and Shang ring (SR) for circumcision in an adult population. Materials and Methods A total of 124 outpatients were randomly assigned to receive PCSD (
Hu Han +3 more
doaj +1 more source
Laparoendoscopic single site surgery in pediatric urology: does it require specialized tools?
International Brazilian Journal of Urology, 2016 Purpose: To describe our experience utilizing Laparoendoscopic single site (LESS) surgery in pediatric urology. Materials and Methods: Retrospective chart review was performed on LESS urologic procedures from November 2009 through March 2013. A total of
Nishant Patel +3 more
doaj +1 more source
Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
Tonsillectomy New Vistas [PDF]
History of tonsillectomy dates back to nearly 2000 years. It was Celsius who first\ud described the procedure in the first century A.D. The potentials for complications after this surgical\ud procedure are still very high despite the advancements in ...
Balasubramanian, Thiagarajan
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