Results 61 to 70 of about 277,157 (310)

Automated High-Throughput Microchannel Assays for Cell Biology: Operational Optimization and Characterization [PDF]

open access: yesJALA: Journal of the Association for Laboratory Automation, 2010
Screening biological readouts in cell culture are increasing in frequency and throughput. In such assays, cell types may be rare and reagents or compounds may be expensive often resulting in a reduced number of conditions and/or replicates. “Tubeless” microfluidics offers a method to reduce this burden, as has been previously shown. In addition the In-
John P, Puccinelli   +2 more
openaire   +2 more sources

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Selection of key sequence-based features for prediction of essential genes in 31 diverse bacterial species. [PDF]

open access: yesPLoS ONE, 2017
Genes that are indispensable for survival are essential genes. Many features have been proposed for computational prediction of essential genes. In this paper, the least absolute shrinkage and selection operator method was used to screen key sequence ...
Xiao Liu   +4 more
doaj   +1 more source

Systematic analyses of a novel circRNA-related miRNAs prognostic signature for Cervical Cancer

open access: yesGenetics and Molecular Biology, 2022
Accumulating evidences shed light on the important roles of Circular RNAs (circRNAs) acting as competing endogenous RNAs (ceRNAs) in cervical cancer (CC) biology.
Shasha Wang, Songying Zhang
doaj   +1 more source

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

Analytical Computational Scheme for Multivariate Nonlinear Time-Fractional Generalized Biological Population Model

open access: yesFractal and Fractional, 2023
This work provides exact and analytical approximate solutions for a non-linear time-fractional generalized biology population model (FGBPM) with suitable initial data under the time-Caputo fractional derivative, in view of a novel effective and ...
Mohammad Alaroud   +3 more
doaj   +1 more source

Control of reaction-diffusion equations on time-evolving manifolds

open access: yes, 2016
Among the main actors of organism development there are morphogens, which are signaling molecules diffusing in the developing organism and acting on cells to produce local responses. Growth is thus determined by the distribution of such signal. Meanwhile,
Duteil, Nastassia Pouradier   +3 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Boundary value problems for systems of non-degenerate difference-algebraic equations

open access: yesVisnik Harkivsʹkogo Nacionalʹnogo Universitetu im. V.N. Karazina. Cepiâ Matematika, Prikladna Matematika i Mehanika, 2019
The study of differential-algebraic boundary value problems was initiated in the works of K. Weierstrass, N.N. Luzin and F.R. Gantmacher. Systematic study of differential-algebraic boundary value problems is devoted to the work of S.
Sergey Chuiko   +2 more
doaj   +1 more source

Effectiveness of Co-Operative Learning on Achievement in Biology

open access: yesIndian Journal of Applied Research, 2011
The present study investigated the effect of cooperative learning on student's achievement in Biology at Higher Secondary level. The sample of the study was 96 students of XI Std. Experimental group was taught using jigsaw method of cooperative learning and to a control group using traditional method.
J. E. Merlin Sasikala   +1 more
openaire   +1 more source

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