Results 61 to 70 of about 2,075,471 (240)

Criterion of positivity for semilinear problems with applications in biology [PDF]

open access: yes, 2017
The goal of this article is to provide an useful criterion of positivity and well-posedness for a wide range of infinite dimensional semilinear abstract Cauchy problems. This criterion is based on some weak assumptions on the non-linear part of the semilinear problem and on the existence of a strongly continuous semigroup generated by the differential ...
arxiv   +1 more source

Building and Managing a Tropical Fish Facility: A Do-It-Yourself Guide [PDF]

open access: yesarXiv, 2023
At the core of most research in zoological disciplines, ranging from developmental biology to genetics to behavioral biology, is the ability to keep animals in captivity. While facilities for traditional model organisms often benefit from well-established designs, construction of a facility for less commonly studied organisms can present a challenge ...
arxiv  

Functional variation among LPMOs revealed by the inhibitory effects of cyanide and buffer ions

open access: yesFEBS Letters, EarlyView.
This study addresses the inhibition of lytic polysaccharide monooxygenases (LPMOs) by cyanide and explains how and why the magnitude of observed inhibitory effects depends on the way LPMO reactions are setup and on the type of LPMO. Enzymes known as lytic polysaccharide monooxygenases (LPMOs) are mono‐copper polysaccharide‐degrading peroxygenases that ...
Ole Golten   +10 more
wiley   +1 more source

An Integrated Approach to Ultrasound Imaging in Medicine and Biology

open access: yes, 2020
Ultrasound (US) imaging is developing rapidly as it enhances the specificity and sensitivity of medical imaging. The disadvantages pertaining to US imaging include dependence on the operator’s skill and equipment, the limited acoustic window in certain ...
Pingtong Huang
semanticscholar   +1 more source

Development and Verification of a Combined Immune- and Metabolism-Related Prognostic Signature for Hepatocellular Carcinoma

open access: yesFrontiers in Immunology, 2022
Immune escape and metabolic reprogramming are becoming important characteristics of tumor biology, which play critical roles in tumor initiation and progression.
Yuanyuan Guo   +10 more
doaj   +1 more source

Immunoregulatory mechanisms of the arachidonic acid pathway in cancer

open access: yesFEBS Letters, EarlyView.
The central role of the arachidonic acid (AA) pathway in anticancer immunity. Enzymes and metabolites of the AA pathway can play both immunosuppressive and immunostimulatory roles in the tumor microenvironment. Therefore, their tailored targeting could be beneficial as a standalone therapy or in combination with current cancer immunotherapy.
Maria Tredicine   +3 more
wiley   +1 more source

Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms

open access: yesFEBS Letters, EarlyView.
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze   +3 more
wiley   +1 more source

Accurate Reaction-Diffusion Operator Splitting on Tetrahedral Meshes for Parallel Stochastic Molecular Simulations [PDF]

open access: yesJournal of Chemical Physics, 2015
Spatial stochastic molecular simulations in biology are limited by the intense computation required to track molecules in space either in a discrete time or discrete space framework, which has led to the development of parallel methods that can take ...
Iain Hepburn, Weiliang Chen, E. Schutter
semanticscholar   +1 more source

Tetracycline-controlled (TetON) gene expression system for the smut fungus Ustilago maydis

open access: yesFrontiers in Fungal Biology, 2022
Ustilago maydis is a biotrophic phytopathogenic fungus that causes corn smut disease. As a well-established model system, U. maydis is genetically fully accessible with large omics datasets available and subject to various biological questions ranging ...
Kishor D. Ingole   +4 more
doaj   +1 more source

Flow‐based immunomagnetic enrichment of circulating tumor cells from diagnostic leukapheresis product

open access: yesMolecular Oncology, EarlyView.
The number of circulating tumor cells obtained from prostate cancer patients was increased approximately 5‐fold compared to regular CellSearch when processing 2 mL diagnostic leukapheresis material aliquots and increased by 44‐fold when processing 20 mL DLA aliquots using the flow enrichment target capture Halbach‐array.
Michiel Stevens   +8 more
wiley   +1 more source

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