Results 81 to 90 of about 70,967 (306)

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

HighDimMixedModels.jl: Robust high-dimensional mixed-effects models across omics data.

PLoS Computational Biology
High-dimensional mixed-effects models are an increasingly important form of regression in which the number of covariates rivals or exceeds the number of samples, which are collected in groups or clusters.
Evan Gorstein, Rosa Aghdam, Claudia Solís-Lemus   +2 more
doaj   +1 more source

A source inverse problem for the pseudo–parabolic equation with the fractional Sturm–Liouville operator

Қарағанды университетінің хабаршысы. Математика сериясы, 2020
A class of inverse problems for restoring the right-hand side of the pseudo-parabolic equation with one fractional Sturm–Liouville operator is considered.
D. Serikbaev, N. Tokmagambetov
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

β-sheet interactions with DNA revealed by the arc repressor-operator complex [PDF]

, 1995
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept.
Raumann, Brigitte Elke
core  

Automated Platforms in C. elegans Research: Integration of Microfluidics, Robotics, and Artificial Intelligence

Micromachines
Caenorhabditis elegans is one of the most extensively studied model organisms in biology. Its advantageous features, including genetic homology with humans, conservation of disease pathways, transparency, short lifespan, small size and ease of ...
Tasnuva Binte Mahbub, Parsa Safaeian, Salman Sohrabi   +2 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Redes de regulação gênica: um modelo integrado da regulação do metabolismo do triptofano em Escherichia coli sob o formalismo de redes de petri [PDF]

, 2006
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia QuímicaVias metabólicas são descritas por um conjunto de reações bioquímicas acopladas por um metabólito intermediário em comum.
Simão, Eugênio
core  

An open-source FACS automation system for high-throughput cell biology.

PLoS ONE
Recent advances in gene editing are enabling the engineering of cells with an unprecedented level of scale. To capitalize on this opportunity, new methods are needed to accelerate the different steps required to manufacture and handle engineered cells ...
Diane M Wiener, Emily Huynh, Ilakkiyan Jeyakumar, Sophie Bax, Samia Sama, Joana P Cabrera, Verina Todorova, Madhuri Vangipuram, Shivanshi Vaid, Fumitaka Otsuka, Yoshitsugu Sakai, Manuel D Leonetti, Rafael Gómez-Sjöberg   +12 more
doaj   +1 more source

Systems Biology Graphical Notation: Process Description language Level 1 Version 2.0

Journal of Integrative Bioinformatics, 2019
The Systems Biology Graphical Notation (SBGN) is an international community effort that aims to standardise the visualisation of pathways and networks for readers with diverse scientific backgrounds as well as to support an efficient and accurate ...
Rougny Adrien, Touré Vasundra, Moodie Stuart, Balaur Irina, Czauderna Tobias, Borlinghaus Hanna, Dogrusoz Ugur, Mazein Alexander, Dräger Andreas, Blinov Michael L., Villéger Alice, Haw Robin, Demir Emek, Mi Huaiyu, Sorokin Anatoly, Schreiber Falk, Luna Augustin   +16 more
doaj   +1 more source