Results 101 to 110 of about 70,967 (306)
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Protein-induced changes in DNA structure and dynamics observed with noncovalent site-directed spin-labeling and PELDOR [PDF]
Site-directed spin labeling and pulsed electron–electron double resonance (PELDOR or DEER) have previously been applied successfully to study the structure and dynamics of nucleic acids. Spin labeling nucleic acids at specific sites requires the covalent
Reginsson, Gunnar Widtfeldt +5 more
core +1 more source
Biosemiotics, code biology, and operational interpretation
Abstract Biosemiotics and code biology are two promising approaches to understanding biological phenomena as meaningful. Biosemiotics proposes that a defining characteristic of life is code-duality, while code biology asserts that the nature of life lies in its code.
openaire +1 more source
Phosphoinositides and inositol phosphates as molecular glues
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Accurate reaction-diffusion operator splitting on tetrahedral meshes for parallel stochastic molecular simulations [PDF]
: Spatial stochastic molecular simulations in biology are limited by the intense computation required to track molecules in space either in a discrete time or discrete space framework, which has led to the development of parallel methods that can take ...
De Schutter, Erik +5 more
core +1 more source
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
An enhanced evolutionary algorithm for detecting complexes in protein interaction networks with heuristic biological operator [PDF]
Detecting complexes in protein interaction networks is one of the most important topics of current computational biology research due to its prominent role in predicting functions of yet uncharacterized proteins and in diseases diagnosis.
Siti Zaiton Mohd Hashim +5 more
core +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
A Note on Solving Matrix Equations Using the Vec Operator [PDF]
This issue was undated. The date given is an estimate.5 pages, 1 article*A Note on Solving Matrix Equations Using the Vec Operator* (Kadane, J. B.; Henderson, H. V.; Searle, S.
Searle, S. R. +5 more
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