Results 111 to 120 of about 1,844,598 (293)

Chromosome segregation dynamics during the cell cycle of Staphylococcus aureus

open access: yesNature Communications
Research on chromosome organization and cell cycle progression in spherical bacteria, particularly Staphylococcus aureus, remains limited and fragmented. In this study, we established a working model to investigate chromosome dynamics in S.
Adrian Izquierdo-Martinez   +8 more
doaj   +1 more source

Scalable workflows for high-throughput respirometry

open access: yesLife Science Alliance
In this study, we discuss the novel methodologies, approaches, and considerations required to scale mitochondrial respirometry studies for high-throughput and large sample number studies.
Corey A Osto   +5 more
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

An integral operator on the classes \(\mathcal{S}^{\ast}(\alpha )\) and \(\mathcal{CVH}(\beta )\)

open access: yes, 2015
The purpose of this paper is to study some properties related to convexity order and coefficients estimation for a general integral operator. We find the convexity order for this operator, using the analytic functions from the class of starlike functions
Ularu, Nicoleta, Breaz, Nicoleta
core   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Synthetic data-driven deep learning for label-free autonomous atomic force microscopy

open access: yesNature Communications
Atomic force microscopy (AFM) is a widely used tool for nanoscale characterization across materials science, energy research, and biology. However, its adoption in high-throughput materials discovery and statistically driven studies remains limited by a ...
Ruben Millan-Solsona   +11 more
doaj   +1 more source

Upper Bounds for the Euclidean Operator Radius and Applications [PDF]

open access: yes, 2006
The main aim of the present paper is to establish various sharp upper bounds for the Euclidean operator radius of an n−tuple of bounded linear operators on a Hilbert space.
Dragomir, Sever S
core   +2 more sources

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Development of a suite of activatable plant synthetic promoter systems using a bacterial LysR-type transcriptional regulator FdeR

open access: yesSynthetic and Systems Biotechnology
Advancing plant synthetic biology requires an abundant supply of orthogonal and tunable genetic parts to express multiple genes simultaneously. Current genetic parts, particularly promoters, used in plants are still limited and often suffer from tissue ...
Yinan Wu, Curtis Chen, Sijin Li
doaj   +1 more source

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